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The photobiomodulation in the bone repair after radiotherapy- experimental study in rats

机译:放射治疗后骨修复中的光调节-大鼠的实验研究

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This research evaluated the effect of the GaAlAs lasertherapy at the healing of surgical wounds produced in Wistar rats femurs few days before the beginning of the radiotherapy. For this, an orifice was artificially produced in the femur bone of the rats and they had been submitted to an external radiotherapy with a radioactive source of cobalt in the dosage of 3000 cGys. The experimental group received additionally seven sessions of 780 nm, 40 mW, 100 J/cm2 or 5 J/cm2 in four points around the surgical wound, at each 48 h, initiated at the day of the surgery. These animals had been sacrificed in three and five weeks. The results show that the number of osteocites (p< 0,0001) and Harvers channels (p< 0,0001) were significantly larger in the groups that had been radiated with laser during the experiment.
机译:这项研究评估了GaAlAs激光疗法对放射治疗开始前几天Wistar大鼠股骨产生的手术伤口愈合的效果。为此,在大鼠的股骨中人工制造了一个孔,并且将它们用放射活性钴以3000 cGys的剂量进行了外部放射治疗。实验组在手术当天开始的每48小时在手术伤口周围的四个点另外接受780 nm,40 mW,100 J / cm2或5 J / cm2的七个疗程。这些动物在三到五个星期内被处死。结果表明,在实验过程中,用激光照射的组中的骨质疏松症(p <0,0001)和Harvers通道(p <0,0001)的数量明显较多。

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