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Development of a knowledge-based simulator for haemodynamic support of septic shock

机译：基于知识的模拟器的开发，用于感染性休克的血流动力学支持

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The authors' previous work has demonstrated self-learning fuzzy control as a powerful, flexible and versatile control technique which adapts itself easily to changing patient conditions. It has never previously been applied to multiple input/output parameter controllers in medicine. The authors are investigating this technique for providing automated control of drug infusions supporting the cardiovascular and renal systems of patients in 'septic shock'. To construct the control system the authors are using this stratagem: modelling the shocked patient; verification of the model; validation of the model; controller strategy development in simulation using the validated model; physical control system development; clinical trials. Here, the authors highlight their validation techniques.

机译：作者的先前工作已经证明了自学习模糊控制是一种强大，灵活且用途广泛的控制技术，可以轻松地适应不断变化的患者状况。以前从未将它应用于医学中的多个输入/输出参数控制器。作者正在研究这种技术，以提供对“脓毒性休克”患者心血管和肾脏系统的药物输注的自动控制。为了构建控制系统，作者正在使用以下策略：对震惊的患者进行建模;模型验证;模型验证;使用已验证的模型在仿真中开发控制器策略;物理控制系统开发;临床试验。在这里，作者重点介绍了他们的验证技术。

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《》|1998年|P.3.1-3.4|共1页
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Ross; J.J.; Mason; D.G.;
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中图分类无线电电子学、电信技术;
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1. ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. [J] . de-Oliveira CF, de-Oliveira DS, Gottschald AF, Intensive care medicine . 2008,第6期

机译：小儿败血性休克的ACCM / PALS血流动力学支持指南：有或没有监测中心静脉血氧饱和度的结果比较。
2. Terlipressin for haemodynamic support in septic shock: Less may be more [J] . Christian Ertmer, Hans-Georg Bone, Hugo Van Aken, Resuscitation. . 2006,第2期

机译：特利加压素在败血性休克中对血流动力学的支持：少则多
3. S-SS criteria: Novel criteria for septic shock and new subset septic shock supported with invasive respiration or vasopressor (SIRV) [J] . Sion Jo, Taeoh Jeong, Jae Baek Lee, Trends in anaesthesia and critical care . 2018,第1期

机译：S-SS标准：用于侵入性呼吸或血管加压器（SIRV）支持的化粪池休克和新的次集休克的新标准（SIRV）
4. Development of a knowledge-based simulator for haemodynamic support of septic shock [C] . Ross J.J., Mason D.G., Institute of Electric and Electronic Engineer IEE Colloquium on Simulation in Medicine . 1998

机译：脓液震动血液力支持的知识模拟器的发展
5. Toward an asymmetric synthesis of 5-fluoronorepinephrine and epinephrine for hemodynamic support during systemic inflammatory response syndrome/septic shock. [D] . Cramer, John Christopher. 2003

机译：在全身性炎症反应综合征/败血性休克期间，寻求5-氟去甲肾上腺素和肾上腺素的不对称合成以提供血流动力学支持。
6. Haemodynamic assessment and support in sepsis and septic shock in resource-limited settings [O] . David Misango, Rajyabardhan Pattnaik, Tim Baker, -1

机译：在资源有限的环境中对败血症和败血性休克进行血流动力学评估和支持
7. Association between Blood Pressure after Haemodynamic Resuscitation in the Prehospital Setting and 28-Day Mortality in Septic Shock [O] . Jouffroy Romain, Anastasia Saade, Pascal Philippe, 2020

机译：血压后血压在血压复苏后的血液压力在预热环境中和脓毒症休克28天死亡率
8. Pharmacologic Support of the Cardiovasculature in Septic Shock. [R] . Chernow, B., Roth, B. L. 1986

机译：感染性休克中心血管系统的药理学支持。

Development of a knowledge-based simulator for haemodynamic support of septic shock

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