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Interaction between the arterial baroreflex and a hypertensive stressor: a mathematical model

机译：动脉压力反射与高血压应激源之间的相互作用：数学模型

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Stressors intensify sympathetic outflow, thus increasing heart rate and arterial blood pressure. The significance of the arterial baroreflex is to be found in reducing such rate and pressure changes. For a better understanding of the interaction between a hypertensive stressor and the arterial baroreflex we have developed a mathematical simulation model, consisting of a hemodynamic section, a baroreceptor section, and a baroreflex section. Physiological or pathological resting conditions are simulated by specific settings of the autonomic tone parameters and cardiac stroke volume. Also the vagal and sympathetic baroreflex gains can be set. A stressor is introduced by adding extra sympathetic outflow to the heart and peripheral resistance. The responses in heart rate and blood pressure help to understand how the arterial baroreflex protects the heart and circulation.
机译：压力源会加剧交感神经流出，从而增加心率和动脉血压。动脉压力反射的重要性在于减少这种速率和压力变化。为了更好地了解高血压压力源和动脉压力反射之间的相互作用，我们开发了一个数学模拟模型，该模型由血液动力学部分，压力感受器部分和压力反射部分组成。通过自主神经张力参数和心脏中风量的特定设置来模拟生理或病理静止状态。还可以设置迷走神经和交感性压力感受反射的获得。通过向心脏和周围阻力增加额外的交感神经引入压力源。心率和血压的反应有助于了解动脉压力反射如何保护心脏和血液循环。

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