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Magnetic handling of droplet in micro chemical analysis system utilizing surface tension and wettability

机译:利用表面张力和润湿性在微化学分析系统中对液滴进行磁处理

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We propose a droplet handling mechanism for micro-chemical analysis systems. We enabled reliable magnetic droplet handling without sample beads sticking to the glass surface by using different liquids' wettability and surface tension. We also developed a separation- and fusion-mechanism of droplets containing beads, and confirmed that our device can effectively condense and rinse the beads by combining the proposed separation and fusion units. The volume of separated droplets containing beads was 30 nl, and we were able to rinse the beads in a series of separation and fusion operations by freshly rinsing droplets 1600 times using the fusion of fresh droplet. The primary advantage of the system is that it doesn't need mechanical devices such as a pump, a valve, and a filter, for handling the solution.
机译:我们提出了一种用于微化学分析系统的液滴处理机制。通过使用不同的液体润湿性和表面张力,我们实现了可靠的磁滴处理,而样品珠不会粘附在玻璃表面上。我们还开发了包含微珠的液滴的分离和融合机制,并确认我们的设备可以通过组合建议的分离和融合单元来有效地凝结和冲洗微珠。包含小珠的分离液滴的体积为30 nl,我们能够通过一系列的分离和融合操作,通过使用新鲜小液滴的融合将小滴新鲜冲洗1600次来冲洗小珠。该系统的主要优点是它不需要机械设备(例如泵,阀门和过滤器)来处理溶液。

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