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Flow Evaluation of Stents in a 180° Curved Tube

机译:180°弯管中支架的流量评估

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摘要

A common therapeutic procedure for treatment of cardiovascular disease is the implantation of stents, in the carotid artery, especially in patients with high risk factors. The procedure is not without risk as clots can be transported into the brain and also re-stenosis occurs in 10-20% of cases. Flow plays a very important role in the success of the implantation. Alterations to flow behavior can lead to clotting and re-stenosis. Slight changes in the flow rate can create velocity fluctuations which are physiologically abnormal. Higher velocity fluctuations and flow separation can lead to shear stresses and recirculation zones, so that platelets aggregate or adhere to the wall. Similar processes might arise just after implantation of stents. We studied flow in four types of stents (a self-X stent, a Wall stent, a covered stent and an improved covered stent) in a silicon rubber model with a 180° bend. We tested the influence of variations in stent design, the direction and mesh of the wires, the in- and outflow, the stretching, surface roughness and the position of the stent, on flow behavior. Of special interest were flow differences between the covered and uncovered stents, the flow resistance, the position of stent in the arterial model and the entrance flow angle.
机译:治疗心血管疾病的常用治疗方法是在颈动脉中植入支架,尤其是在高危因素患者中。该过程并非没有风险,因为血凝块可以转运到大脑中,并且在10-20%的病例中还会发生再狭窄。流动在成功植入中起着非常重要的作用。流动行为的改变可导致凝血和再狭窄。流速的轻微变化会产生生理上异常的速度波动。较高的速度波动和流动分离会导致剪切应力和再循环区域,从而使血小板聚集或粘附在壁上。植入支架后可能会发生类似的过程。我们在180°弯曲的硅橡胶模型中研究了四种类型的支架(自X支架,Wall支架,覆盖式支架和改进的覆盖式支架)的流动性。我们测试了支架设计,钢丝的方向和网格,流入和流出,拉伸,表面粗糙度和支架位置的变化对流动行为的影响。特别令人关注的是,覆盖的和未覆盖的支架之间的流量差异,流动阻力,支架在动脉模型中的位置以及入口流动角度。

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