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Localization correlation and visualization of electroencephalographic surface electrodes and brain anatomy in epilepsy studies

机译:癫痫研究中脑电图表面电极和脑解剖学的定位相关性与可视化

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Advances in neuroimaging have enhanced the clinician's ability to localize the epileptogenic zone in focal epilepsy, but 20-50 percent of these cases still remain unlocalized. Many sophisticated modalities have been used to study epilepsy, but scalp electrode recorded electroencephalography is particularly useful due to its noninvasive nature and excellent temporal resolution. This study is aimed at specific locations of scalp electrode EEG information for correlation with anatomical structures in the brain. 3D position localizing devices commonly used in virtual reality systems are used to digitize the coordinates of scalp electrodes in a standard clinical configuration. The electrode coordinates are registered with a high- resolution MRI dataset using a robust surface matching algorithm. Volume rendering can then be used to visualize the electrodes and electrode potentials interpolated over the scalp. The accuracy of the coordinate registration is assessed quantitatively with a realistic head phantom.
机译:神经影像动物的进展增强了临床医生在局灶性癫痫中定位癫痫区域的能力,但其中20-50%的这些病例仍然没有百分比。许多复杂的方式已经用于研究癫痫,但是头皮电极记录的脑电图由于其非侵入性自然和优异的时间分辨率而特别有用。本研究旨在针对头皮电极EEG信息的特定位置,用于与大脑中的解剖结构相关。虚拟现实系统中常用的3D位置定位设备用于在标准临床配置中向头皮电极的坐标进行数字化。使用鲁棒表面匹配算法,在高分辨率MRI数据集中注册电极坐标。然后可以使用体积渲染来可视化在头皮上插入的电极和电极电位。坐标注册的准确性定量地评估了一个现实的头部幻像。

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