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首页> 外文会议>International conferenc on rare earth development and applications >MALE REPRODUCTIVE TOXICITY OF YTTRIUM CHLORIDE ON RATS AFTER ORAL ADMINISTRATION
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MALE REPRODUCTIVE TOXICITY OF YTTRIUM CHLORIDE ON RATS AFTER ORAL ADMINISTRATION

机译：口服后氯化钇对大鼠的男性生殖毒性

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For the identification of male reproductive hazard of yttrium, Wistar rats were gavaged with 4-400mg YCl_3/kg/d,5d/wk for 3 months. Caudal epididymal sperm characteristice,plasma and testicu-lar testosterone concentrations, and pathology of reproductive organs were examined The results showed only a trend of dose-effect dependent slight decrease in body weight gain in 40 and 400 mg YCl_3/kg groups. Epididymis/body weight ratio and percentage of high swimming speed sperm in 400 mg YCl_3/kg group were higher than those of saline control group,while its sperm malformation rate was slightly lower In conclusion, YCl_3, after oral administration,had no obvious male reproductive toxicity on rats.
机译：为了鉴定钇的雄性生殖危害，对Wistar大鼠灌胃4-400mg YCl_3 / kg / d，5d / wk 3个月。检查了尾附睾精子的特征，血浆和睾丸睾丸激素的浓度，以及生殖器官的病理学。结果表明，剂量增加依赖剂量效应的趋势在40和400 mg YCl_3 / kg组略有下降。 400 mg YCl_3 / kg组附睾/体重比和高泳速精子百分率高于生理盐水对照组，但精子畸形率略低。结论：口服后YCl_3男性无明显生殖能力对大鼠有毒性。

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