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Ventricular mechanics in a transgenic mouse model of familial hypertrophic cardiomyopathy

机译：家族性肥厚型心肌病转基因小鼠模型的心室力学

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An isolated ejecting mouse heart preparation was developed to examine the relationship between local myocyte disarray associated with familial hypertrophic cardiomyopathy (FHC) and alterations in regional mechanics. Nonhomogeneous strain analysis showed that surface strains in the transgenic mouse hearts were more nonuniform than normal controls possibly due to focal/local myocyte disarray or fibrosis.

机译：开发了一种隔离的射出小鼠心脏制剂，以检查与家族性肥厚性心肌病（FHC）相关的局部心肌细胞紊乱与区域力学改变之间的关系。非均质菌株分析表明，转基因小鼠心脏中的表面菌株比正常对照更不均匀，这可能是由于局灶性/局部性心肌细胞紊乱或纤维化所致。

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《Bioengineering conference》|1997年|p.469-470|共2页
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William J. Karlon; James W. Covell; Andrew D. McCulloch; Jeffrey H. Omens;
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中图分类基础医学;
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1. Early remodeling of repolarizing K+ currents in the alpha MHC403/+ mouse model of familial hypertrophic cardiomyopathy [J] . Hueneke Rocco, Adenwala Adam, Mellor Rebecca L., Journal of Molecular and Cellular Cardiology . 2017,第期

机译：αMHC403/ +家族肥厚性心肌病变αMHC403/ +鼠标模型中的早期重塑k +电流
2. Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice. [J] . Abraham TP, Jones M, Kazmierczak K, Cardiovascular Research . 2009,第1期

机译：家族性肥厚性心肌病转基因模型小鼠的舒张功能障碍。
3. Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice [J] . Theodore P. Abraham1 Michelle Jones2 Katarzyna Kazmierczak2 Hsin-Yueh Liang1 Aurelio C. Pinheiro1 Cory S. Wagg3 Gary D. Lopaschuk3 and Danuta Szczesna-Cordary2* Cardiovascular Research . 2009,第1期

机译：家族性肥厚性心肌病转基因模型小鼠的舒张功能障碍
4. Ventricular mechanics in a transgenic mouse model of familial hypertrophic cardiomyopathy [C] . William J. Karlon, James W. Covell, Andrew D. McCulloch, Bioengineering conference . 1997

机译：家族肥厚性心肌病的转基因小鼠模型中的心室力学
5. Single molecule kinetics in familial hypertrophic cardiomyopathy transgenic heart. [D] . Mettikolla, Yalla Vara Prasad. 2010

机译：家族性肥厚型心肌病转基因心脏的单分子动力学。
6. Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice [O] . W. Glenn L. Kerrick, Katarzyna Kazmierczak, Yuanyuan Xu, -1

机译：心室肌球蛋白调节性轻链中的恶性家族性肥厚型心肌病D166V突变对转基因小鼠的皮肤和完整乳头肌纤维产生深远影响
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Ventricular mechanics in a transgenic mouse model of familial hypertrophic cardiomyopathy

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