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Ultrasonic, Spectrum-Analysis, Tissue-Typing Images for Prostate-Biopsy Guidance and Staging

机译:超声,频谱分析,组织分型图像,用于前列腺活检的指导和分期

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Prostate cancer is diagnosed using needle biopsies guided by conventional ultrasonic images. However, conventional ultrasound has inadequate sensitivity and specificity to direct biopsies reliably into cancerous regions. Urologists use conventional images to guide the needle systematically, but "blindly", into six or more selected regions of the gland. Unless a distinctly palpable or ultrasonically visible nodule is present (e.g, as a hypoechogenic region) to raise suspicion, the urologist simply samples tissue from the left and right base, mid, and apical regions of the gland, and possibly from the transition zone or seminal vesicles. Becasue of the blind nature of this procedure, initial biopsies miss about half the cancers, which reslts in a high incidence of false-negative biopsies; in addition, more than two thirds of the initial biopsies sample benign tissue, which reslts in an unfortunately high incidence of true negative biopsies.
机译:使用常规超声图像引导的穿刺活检诊断前列腺癌。然而,常规超声具有不足以将活检可靠地引导到癌变区域的敏感性和特异性。泌尿科医师使用常规图像将针头系统地但“盲目地”引导到腺体的六个或更多选定区域。除非存在明显可触及或超声可见的结节(例如,作为低回声区)引起怀疑,否则泌尿科医师仅从腺体的左,右基部,中部和根尖区域以及可能从过渡带或精囊。由于该过程的盲目性,最初的活组织检查错过了大约一半的癌症,这导致假阴性活组织检查的发生率很高。此外,超过三分之二的初始活检样本是良性组织,不幸的是,真正的阴性活检样本的发生率很高。

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