Bacterial symbionts of the bryostatin-producting bryozoan bugula neritina

机译：产生抑菌素的布氏菌布氏菌的细菌共生体

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Bugula neritina (Cheilostomata, Cellularoidea) is an arborescent bryozoan with a cosmopolitan distribution in temperate marine waters. Bugula neritina is a subject of current research interest because it is the source of the bryostatins (Pettit, 1991) a family of cytotoxic macrocyclic lactones, one of which, bryostatin 1, is currently in clinical trials for treatment of cancer (Jayson et al., 1995; Philip et al., 1993; Prendiville et al., 1993). Many bryozoans produce alkaloids (Anthoni et al., 1990) presumably as a chemical defense, but B. neritina is the only bryozoan currently known to produce complex polyketides. Polyketides are compounds typically produced by actinomycetes and fungi, and in at least one case by a proteobacterium (Schupp et al., 1995).

机译：Bugula neritina（Cheilostomata，Cellularoidea）是树状苔藓虫，在温带海水中具有世界性分布。臭虫（Bugula neritina）是当前研究关注的主题，因为它是细胞抑制性大环内酯家族（bryostatins）的来源（Pettit，1991），其中一种是bryostatin 1，目前正处于临床治疗癌症的研究中（Jayson et al。，1995; Philip等，1993; Prendiville等，1993）。许多苔藓动物产生生物碱（Anthoni等，1990），大概是一种化学防御作用，但是neuro B. neritina是目前已知的唯一会产生复杂聚酮化合物的苔藓动物。聚酮化合物是通常由放线菌和真菌，至少在一种情况下由变形杆菌产生的化合物（Schupp等，1995）。

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《International marine biotechnology conference》|1998年|p.281-284|共4页
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Margo G. Haygood; Seana K. Davidson;
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1. bryA: An unusual modular polyketide synthase gene from the uncultivated bacterial symbiont of the marine bryozoan Bugula neritina [J] . Hildebrand M, Waggoner LE, Liu HB, Chemistry & biology . 2004,第11期

机译：bryA：来自海洋苔藓虫Bugula neritina的未经培养的细菌共生体的不寻常的模块化聚酮化合物合酶基因
2. Identification of Sibling Species of the Bryozoan Bugula neritina That Produce Different Anticancer Bryostatins and Harbor Distinct Strains of the Bacterial Symbiont "Candidatus Endobugula sertula" [J] . Seana K. Davidson, Margo G. Haygood The Biological Bulletin . 1999,第3期

机译：产生不同的抑菌抑菌素和细菌共生体“内生梭菌”的港口不同菌株的苔藓苔藓菌同胞种的鉴定。
3. Small-subunit rRNA genes and in situ hybridization with oligonucleotides specific for the bacterial symbionts in the larvae of the bryozoan Bugula neritina and proposal of "Candidatus endobugula sertula". [J] . M G Haygood, S K Davidson Applied and Environmental Microbiology . 1997,第11期

机译：小亚基rRNA基因和原位杂交与特定于细菌的Bugula neritina幼虫中细菌共生体的寡核苷酸和“ Candidatus endobugula sertula”的提议。
4. Bacterial symbionts of the bryostatin-producting bryozoan bugula neritina [C] . Margo G. Haygood, Seana K. Davidson International marine biotechnology conference . 1998

机译：Bryostatin-Produceing Bryozoan Budula Neritina的细菌共生
5. A molecular study of larval metamorphosis in the marine bryozoan Bugula neritina. [D] . Wong, Yue Him. 2012

机译：对海洋苔藓虫Bugula neritina幼虫变态的分子研究。
6. Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont Candidatus Endobugula sertula of the Bryozoan Bugula neritina [O] . S. K. Davidson, S. W. Allen, G. E. Lim, 2001

机译：苔藓菌Bugula neritina的细菌共生菌 Candidatus Endobugula sertula对苔藓抑素进行生物合成的证据。
7. bryA An Unusual Modular Polyketide Synthase Gene from the Uncultivated Bacterial Symbiont of the Marine Bryozoan Bugula neritina [O] . Hildebrand Mark, Waggoner Laura E., Liu Haibin, 2004

机译：bryA来自海洋苔藓虫的未培养细菌共生体的异常模块化聚酮化合物合酶基因

Bacterial symbionts of the bryostatin-producting bryozoan bugula neritina

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