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首页> 外文会议>International symposium on ceramics in medicine >Bone-bonding ability to titanium metal chemically treated with hydrogen peroxide containing tantalum chloride: in vivo examination
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Bone-bonding ability to titanium metal chemically treated with hydrogen peroxide containing tantalum chloride: in vivo examination

机译：用含氯化钽的过氧化氢化学处理的钛金属的骨结合能力：体内检查

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Apatite formation on implants is important to achieve bone-binding. Ohtsuki et al. showed that titanium metal chemically treated with hydrogenperoxide solution containing tantalum chlorides has an ability to form hydroxyapatite layer in a simulated body fluid (Kokubo solution) which had an inorganic ion composition similar to human blood plasma. In our study, titanium cylinder (4.0mm in diameter and 20.0mm in length) treated with Ohtsuki's method was implanted into a hole (4.2mm in diameter) in rabbit's tibia. 4, 8, 12 and 16 weeks after surgery, push-out test was performed to evaluate the shearing force between the titanium metal and bone tissue. The result was compared with those of non-treated titanium. 8 weeks after surgery, shearing force of the treated titanium was significantly stronger than those of the non-treated titanium. Scanning electron microscopic (SEM) observation and energy dispersive X-ray microanalysis (EDX) showed a Ti gellayer on the surface of the treated titanium and the layer corrected directly to bone tissue. Morever, the shearing force was higher in 4.0mm-hole than that for in 4.2mm-hole for sample-implanted. Thus the titanium implants treated with the hydrogenperoxide solution containing tantalum chlorides had bioactivity in vivo.
机译：植入物上磷灰石的形成对于实现骨结合很重要。大月等。结果表明，用含有氯化钽的过氧化氢溶液化学处理的钛金属具有在模拟体液（小久保溶液）中形成羟磷灰石层的能力，该体液具有类似于人体血浆的无机离子成分。在我们的研究中，将经过Ohtsuki方法处理的钛圆柱体（直径4.0毫米，长度20.0毫米）植入兔子胫骨的一个洞（直径4.2毫米）中。手术后第4、8、12和16周，进行推出试验以评估钛金属与骨组织之间的剪切力。将结果与未处理的钛进行了比较。手术后8周，处理过的钛的剪切力明显强于未处理过的钛。扫描电子显微镜（SEM）观察和能量色散X射线显微分析（EDX）显示，在处理过的钛表面上有一层Ti凝胶层，该层直接校正了骨组织。此外，样品植入的4.0mm孔的剪切力比4.2mm孔的剪切力高。因此，用含有氯化钽的过氧化氢溶液处理的钛植入物在体内具有生物活性。

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