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In vivo evaluation of resorption, bone matrix osteoclastic and deposition and estimation of osteoblastic activity of biocement d in a cancellous bone defect

机译:在松质骨缺损中体内吸收,骨基质破骨和沉积的评估以及生物水泥d的成骨活性评估

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Biocement D, a newly developed calcium phosphate based cement was implanted in a rabbit defect model. Eight weeks after implantation histology revealed no signs of inflammation. The resorption of the cement through ostcoclasts and concomitant new bone formation through osteoblasts seems to mimic the natural remodeling of bone. Osteoclastic activity was determined by histochemical staining of the tartrate-resistant-acidic-phosphatase (TRAP), osteoblastic activity by alcaline-phosphatase (APh) staining and bone matrix formation by means of osteocalcin detection.
机译:Biocement D(一种新开发的磷酸钙基水泥)被植入兔子缺损模型中。植入后八周,组织学未见发炎迹象。通过破骨细胞对水泥的吸收以及通过成骨细胞伴随的新骨形成似乎模仿了骨的自然重塑。通过抗酒石酸酸性磷酸酶(TRAP)的组织化学染色,通过碱性磷酸酶(APh)染色的成骨细胞活性以及通过骨钙素检测的骨基质形成来测定破骨细胞活性。

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