GALACTOSYLATED CHITOSAN-DNA NANOPARTICLES PREPARED USING WATER-SOLUBLE CHITOSAN AS A GENE CARRIER

机译：以水溶性壳聚糖为基因载体制备半乳糖化壳聚糖DNA纳米颗粒

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Galactosylated chitosan-DNA nanoparticles were prepared using water-soluble chitosan(WSC) as a non-viral vector. The sizes, turbidity, morphology, electrophoretic mobility and cytotoxicity were studied. Also, transfection efficiency of galactosylated chitosan-DNA complexes were compared between HepG2 which has asialoglycoprotein receptors(ASGR) and Hela without ASGR.

机译：使用水溶性壳聚糖（WSC）作为非病毒载体制备了半乳糖基化的壳聚糖-DNA纳米颗粒。研究了大小，浊度，形态，电泳迁移率和细胞毒性。此外，比较了半乳糖基化壳聚糖-DNA复合物的转染效率，该反应在具有去唾液酸糖蛋白受体（ASGR）的HepG2和不具有ASGR的Hela之间进行了比较。

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《Proceedings of the 29th Annual Meeting of the Controlled Release Society》|2002年|p.1421-1422|共2页
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T. H. Kim; I. K. Park; J. W. Nah; T. Akaike; C. S. Cho;
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中图分类化学工业;
关键词
gene carrier; cationic polymer; water-soluble chitosan; galactosylated chitosan-DNA nanoparticles; asialoglycoprotein receptor;

机译：基因载体;阳离子聚合物;水溶性壳聚糖;半乳糖基化壳聚糖-DNA纳米颗粒;亚糖蛋白受体;

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专利

1. Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. [J] . Kim TH, Park IK, Nah JW, Biomaterials . 2004,第17期

机译：使用水溶性壳聚糖作为基因载体制备的半乳糖基化壳聚糖/ DNA纳米颗粒。
2. Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. [J] . Kim TH, Park IK, Nah JW, Biomaterials . 2004,第17期

机译：使用水溶性壳聚糖作为基因载体制备的半乳糖基化壳聚糖/ DNA纳米颗粒。
3. Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency [J] . Mao HQ., Troung-Le VL., Janes KA., Journal of Controlled Release: Official Journal of the Controlled Release Society . 2001,第3期

机译：壳聚糖-DNA纳米颗粒作为基因载体：合成，表征和转染效率
4. GALACTOSYLATED CHITOSAN-DNA NANOPARTICLES PREPARED USING WATER-SOLUBLE CHITOSAN AS A GENE CARRIER [C] . T. H. Kim, I. K. Park, J. W. Nah, Annual meeting of the Controlled Release Society . 2002

机译：使用水溶性壳聚糖作为基因载体制备半乳糖基化的壳聚糖-DNA纳米粒子
5. Chitosan-DNA nanoparticles: Synthesis, characterization, subcellular transport and oral delivery of genetic vaccines. [D] . Roy, Krishnendu. 2000

机译：壳聚糖-DNA纳米颗粒：遗传疫苗的合成，表征，亚细胞运输和口服递送。
6. Evaluation of In Vivo Transfection Efficiency of Eudragit Coated Nanoparticles of Chitosan-DNA: A pH-sensitive System Prepared for Oral DNA Delivery [O] . Sedigheh Momenzadeh, Abdorrahim Sadeghi, Nasimeh Vatandoust, 2015

机译：评价Eudragit包被的壳聚糖-DNA纳米粒子的体内转染效率：制备用于口服DNA传递的pH敏感系统。
7. Efficient Nonviral Gene Therapy Using Folate-Targeted Chitosan-DNA Nanoparticles In Vitro [O] . Jreyssaty, Christian, Shi, Qin, Wang, Huijie, 2012

机译：叶酸靶向壳聚糖-DNA纳米粒子的体外有效非病毒基因治疗。

GALACTOSYLATED CHITOSAN-DNA NANOPARTICLES PREPARED USING WATER-SOLUBLE CHITOSAN AS A GENE CARRIER

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