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Progress towards Incorporation of Antimicrobial Peptides for Disease Resistance in Citrus

机译:柑橘抗病抗菌肽掺入的研究进展

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Antimicrobial peptides play important roles in the innate immune response and can be found to occur in all classes of life, including humans. These peptides are usually small proteins and have an ability to associate with bacterial cell membranes. Antimicrobial peptides are also characterized by their broad spectrum antibiotic property. Citrus canker and Huanglongbing (HLB) are the two major diseases threatening the global citrus industry. All commercial grapefruit, sweet orange and tangerine cultivars are susceptible to these diseases, and it is difficult to create tolerant cultivars via conventional breeding. Incorporation of one or more genes encoding for antimicrobial peptides into the citrus genome via genetic engineering could potentially result in development of cultivars resistant to these diseases, without modifying the varietal fidelity.
机译:抗菌肽在先天免疫应答中起着重要作用,并且发现其存在于包括人类在内的所有生活类别中。这些肽通常是小蛋白质,具有与细菌细胞膜缔合的能力。抗菌肽还具有广谱抗菌特性。柑橘溃疡病和黄龙病(HLB)是威胁全球柑橘产业的两种主要疾病。所有的商业葡萄柚,甜橙和橘子品种都容易受到这些疾病的影响,因此很难通过常规育种产生耐性品种。通过基因工程将编码抗微生物肽的一种或多种基因掺入柑橘基因组中可能潜在地导致对这些疾病具有抗性的品种的发展,而不改变品种的保真度。

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