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Improved method for predicting polyp location from CT colonography for optical colonoscopy

机译:改进的从结肠镜检查结肠息肉位置的光学结肠镜检查方法

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The ability to accurately locate a polyp found on computed tomographic colonography (CTC) at subsequent optical colonoscopy (OC) is an important part of CTC for colorectal cancer screening. A previous study has shown that a polyp''s normalized distance along the colon centerline (NDACC) derived from CTC data can be utilized to predict its location at OC. We present a novel and automated method using a high degree uniform B-Spline curve fitting of the colon centerline on CTC to simulate OC colonoscope paths in order to more accurately predict polyp position. This evaluation is to determine whether the B-Spline method produces statistically significant improvement over the NDACC method in terms of prediction errors within 5 and 10 cm (± 1 colonoscope mark). Two-tailed Fisher''s Exact Tests indicate the B-Spline method is superior to the NDACC method, especially for locating polyps in the central portion of the colon. The ability to predict polyp locations within 5 and 10 cm increased 31.5 % and 10.2 % respectively using the B-Spline method.
机译:在随后的光学结肠镜检查(OC)上准确定位在计算机断层扫描结肠造影(CTC)上发现的息肉的能力,是结肠直肠癌筛查中CTC的重要组成部分。先前的研究表明,从CTC数据得出的息肉沿结肠中心线(NDACC)的标准化距离可用于预测其在OC处的位置。我们提出了一种新颖且自动化的方法,该方法使用CTC上结肠中心线的高度均匀B样条曲线拟合来模拟OC结肠镜检查路径,以便更准确地预测息肉位置。这项评估是为了确定B样条法相对于NDACC方法是否在5厘米和10厘米(±1个结肠镜检查标记)范围内的预测误差方面产生统计学上显着的改善。两尾费舍尔精确测试表明,B样条方法优于NDACC方法,尤其是在结肠中央部位定位息肉时。使用B样条法预测5厘米和10厘米内息肉位置的能力分别提高了31.5%和10.2%。

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