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Toward tetherless insufflation of the GI Tract

机译:进行胃肠道的无约束充气

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摘要

Toward increasing the diagnostic ability of wireless capsule endoscopy, we propose a method to wirelessly insufflate the Gastrointestinal Tract. By increasing the viewable surface area, it appears likely that capsule-based insufflation may reduce the number of false negative diagnoses made by endoscopic capsules. Our approach to wireless insufflation is to utilize controlled phase transition of a small volume of fluid stored onboard the capsule to a large volume of gas that is then emitted into the intestine. We begin by describing experiments designed to evaluate the amount of gas a capsule must produce to have a beneficial impact on visualization in the colon. We then describe experiments evaluating how much gas can be generated from a given volume of fluid, using Hydrogen Peroxide as our working fluid. We also evaluate thermal effects of the Hydrogen Peroxide reaction. The cumulative result of these experiments is an illustration of the feasibility of carrying a sufficient volume of fluid onboard a wireless capsule to generate a beneficial enhancement in visualization of the interior of the Gastrointestinal Tract, and specifically the colon.
机译:为了提高无线胶囊内窥镜的诊断能力,我们提出了一种无线吹入胃肠道的方法。通过增加可见的表面积,基于胶囊的吹入似乎可以减少内窥镜胶囊做出的假阴性诊断的次数。我们进行无线吹入的方法是利用胶囊中存储的少量液体到大量气体的受控相变,然后将其排放到肠中。我们从描述旨在评估胶囊必须产生的气体量以对结肠可视化产生有益影响的气体的实验开始。然后,我们描述使用过氧化氢作为我们的工作流体来评估从给定体积的流体中可以产生多少气体的实验。我们还评估了过氧化氢反应的热效应。这些实验的累积结果说明了在无线胶囊上携带足够量的液体以在胃肠道(尤其是结肠)内部的可视化方面产生有益增强的可行性的例证。

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