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Linguistic Analysis of Genomic Islands Revealed Recent Acquisition of Genetic Materials by Mycobacterium tuberculosis from alpha-Proteobacteria

机译:基因组岛的语言分析揭示了结核分枝杆菌从α-变形杆菌中获得的遗传物质的最新信息

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Important genes may flux among bacteria by horizontal transfer and trigger substantial evolutionary changes. Novel genome linguistic and visualization approaches helped to identify genomic islands in Mycobacterium tuberculosis and trace their origin down to alpha-Proteobacteria. The identified genomic islands are distinctive from prophage inserts common for Mycobacteria. Donor-recipient relationships were visualized for the analysis on a two-dimensional map. A database of genomic islands found in bacterial chromosomes has been created and it is freely available on-line at http://anjie.bi.up.ac.za/geidb/geidb-home.php.
机译:重要的基因可能通过水平转移在细菌之间流通,并引发实质性的进化变化。新颖的基因组语言和可视化方法有助于鉴定结核分枝杆菌中的基因组岛并将其起源追溯到α-变形杆菌。所鉴定的基因组岛与分枝杆菌常见的噬菌体插入物不同。在二维地图上可视化了供体与受体之间的关系,以进行分析。已经建立了在细菌染色体中发现的基因组岛的数据库,该数据库可从http://anjie.bi.up.ac.za/geidb/geidb-home.php在线免费获得。

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