PSE in Pharmaceutical Process Development

机译：制药工艺开发中的PSE

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The pharmaceutical industry is under growing pressure to increase efficiency, both in production and in process development. This paper will discuss the use of Process Systems Engineering (PSE) methods in pharmaceutical process development, and searches for answers to questions such as: Which PSE methods can be applied readily? Where is more method development needed? The paper is illustrated with a series of short examples taken from the literature and ongoing research projects.

机译：制药行业在提高生产和工艺开发效率方面面临越来越大的压力。本文将讨论在制药过程开发中使用过程系统工程（PSE）方法的问题，并寻找诸如以下问题的答案：哪种PSE方法可以很容易地应用？在哪里需要更多的方法开发？本文用一系列简短的例子进行了说明，这些例子摘自文献和正在进行的研究项目。

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《European symposium on computer aided process engineering;ESCAPE 21》|2012年|p.1628-1632|共5页
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Krist V. Gernaey; Albert E. Cervera; John M. Woodley;
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中图分类信息处理（信息加工）;信息处理（信息加工）;
关键词
design space; pharmaceutical production; process development; PSE;

机译：设计空间;药品生产;工艺开发; PSE;

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专利

1. A perspective on PSE in pharmaceutical process development and innovation [J] . Krist V. Gernaey, Albert E. Cervera-Padrell, John M. Woodley Computers & Chemical Engineering . 2012,第Jula11期

机译：PSE在制药工艺开发和创新中的前景
2. Continuous processing and the applications of online tools in pharmaceutical product manufacture: Developments and examples [J] . OoiS.M., SarkarS., VanVarenberghG., Therapeutic delivery . 2013,第4期

机译：连续加工和在线工具在医药产品制造中的应用：发展和实例
3. Active pharmaceutical ingredient (API) production involving continuous processes - A process system engineering (PSE)-assisted design framework [J] . European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2012,第2期

机译：涉及连续过程的活性药物成分（API）生产-过程系统工程（PSE）辅助设计框架
4. PSE in Pharmaceutical Process Development [C] . Krist V. Gernaey, Albert E. Cervera, John M. Woodley European Symposium on Computer Aided Process Engineering . 2011

机译：PSE在药物过程开发中
5. Process systems engineering methods for the development of continuous pharmaceutical manufacturing processes. [D] . Rogers, Amanda J. 2015

机译：用于开发连续药物制造工艺的工艺系统工程方法。
6. Modeling Prion-Like Processing of Tau Protein in Alzheimer’s Disease for Pharmaceutical Development [O] . Claude M. Wischik, Björn O. Schelter, Damon J. Wischik, -1

机译：模拟阿尔茨海默氏病中类似于Tau蛋白的Prion加工过程以进行药物开发
7. Gernaey K.V. (2012) Development of continuous pharmaceutical production processes supported by PSE methods and tools. The Scale-Up of Chemical Processes Conference, Baveno, Italy, July 9-11, 2012. [O] . Gernaey Krist 2012

机译：Gernaey K.V. （2012）开发由psE方法和工具支持的连续药物生产过程。化学过程放大会议，Baveno，意大利，2012年7月9 - 11日。

PSE in Pharmaceutical Process Development

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