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首页> 外文会议>International ISA biomedical sciences instrumentation symposium;Annual rocky mountain bioengineering symposium >A PILOT STUDY ON THE EFFECT OF ACUTE TAI CHI PRACTICE ON PERIPHERAL BLOOD CYTOKINE EXPRESSION IN HEALTHY VOLUNTEERS
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A PILOT STUDY ON THE EFFECT OF ACUTE TAI CHI PRACTICE ON PERIPHERAL BLOOD CYTOKINE EXPRESSION IN HEALTHY VOLUNTEERS

机译：急性太极拳练习对健康志愿者外周血细胞因子表达影响的初步研究

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Purpose: Tai chi (TC) is a unique form of exercise having both mind and body components - focused mindfulness and physical movement. It is perhaps best known for its ability to prevent falls in elderly people. It is also thought to improve vitality, longevity, mental and physical health. Recent studies have demonstrated its effectiveness as an intervention for chronic diseases associated with the inflammatory process, such as arthritis, heart disease, diabetes, and obesity. The objective of this study was to explore the modulatory effect of acute TC practice on anti-inflammatory cytokine levels in healthy volunteers. Design: This study used a pre-and post-treatment, quasi-experimental design. Blood samples were collected from 7 healthy Yang style TC practitioners before and immediately after one-hour of TC practice. Plasma cytokine levels were measured using RayBiotech semi-quantitive inflammatory cytokine array kit. To fully understand the protein array results in the plasma sample, mRNA was isolated from peripheral blood mononuclear cells (PBMCs) and analyzed using die SABiosciences inflammatory cytokine PCR array. Results: The result indicated a significant increase of the anti-inflammatory cytokine interleukin 13 (IL-13) in the 7 subjects' plasma after one-hour of TC practice (average increase 6.89+4.50 fold). mRNA of three subjects (Player 4, 5 and 7) passed the quality control and were analyzed. The results indicated 1.89 fold up-regulation of IL-13 mRNA from PBMC. Conclusion: The results from this pilot study combined with studies exploring the effect of TC on heart rate variability indicate that positive health effects attributed to TC practice may be linked to activation of the anti-inflammatory pathway.
机译：目的：太极拳（TC）是一种独特的运动形式，兼具身心功能-专注于正念和身体运动。它以防止老年人跌倒的能力而闻名。人们还认为可以改善活力，寿命，精神和身体健康。最近的研究表明其作为干预与炎症过程相关的慢性疾病（如关节炎，心脏病，糖尿病和肥胖症）的有效性。这项研究的目的是探讨急性TC实践对健康志愿者体内抗炎细胞因子水平的调节作用。设计：本研究采用了前处理和后处理的准实验设计。在进行1小时的TC训练之前和之后，立即从7位健康的杨式TC训练者那里采集了血液样本。使用RayBiotech半定量炎症细胞因子阵列试剂盒测量血浆细胞因子水平。为了充分了解血浆样品中的蛋白质阵列结果，从外周血单核细胞（PBMC）中分离了mRNA，并使用SABiosciences炎性细胞因子PCR阵列进行了分析。结果：结果表明，在进行TC实践一小时后，7名受试者血浆中的抗炎细胞因子白介素13（IL-13）显着增加（平均增加6.89 + 4.50倍）。 3名受试者（第4、5和7层）的mRNA通过了质量控制并进行了分析。结果表明来自PBMC的IL-13 mRNA的1.89倍上调。结论：这项前瞻性研究的结果与探索TC对心率变异性的研究相结合的结果表明，TC实践对健康的积极影响可能与抗炎途径的激活有关。

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