首页> 外文会议>World biomaterials congress >Suppression of tumor growth in H-ras liver cancer model mice by programmed cell death 4 gene delivery using galactosylated poly(ethylene glycol)-chitosan-graft-spermine
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Suppression of tumor growth in H-ras liver cancer model mice by programmed cell death 4 gene delivery using galactosylated poly(ethylene glycol)-chitosan-graft-spermine

机译:半乳糖基化聚乙二醇-壳聚糖-接枝-精胺通过程序性细胞死亡4基因传递抑制H-ras肝癌模型小鼠的肿瘤生长

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The copolymer was shown to efficiently form complexes with DNA and to have the appropriate physicochemical properties to deliver genes into hepatocytes. This copolymer had low cytotoxicity and exhibited high levels of gene expression efficiency in vitro and in vivo.
机译:共聚物被证明可以有效地与DNA形成复合物,并具有适当的物理化学性质,可以将基因传递到肝细胞中。该共聚物具有低细胞毒性,并且在体外和体内表现出高水平的基因表达效率。

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