Proportional hazard model for time-dependent covariates with repeated events

机译：具有重复事件的时间相关协变量的比例风险模型

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Cox's proportional hazard is potentially the most used method in life data and survival analysis. Although the method is relatively simple to understand, its major difficulties in estimation are observed when time dependent-covariates with repeated events are used as input variables. This paper presents a review and analysis of the model parameter estimation. The model's assumptions are discussed, and a detailed analysis highlights the application, advantages and potential limitations when the assumption of proportionality is violated.

机译：考克斯的比例风险可能是生命数据和生存分析中使用最多的方法。尽管该方法相对易于理解，但是当将具有重复事件的时间相关协变量用作输入变量时，会发现其估计方面的主要困难。本文对模型参数估计进行了回顾和分析。讨论了模型的假设，并进行了详细分析，突出了违反比例假设时的应用，优点和潜在限制。

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《ISSAT international conference on reliability quality in design》|2012年|258-262|共5页
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Alexandre Mendes; Nasser Fard;
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Proportional hazard model; Cox model; time-dependent covariates; repeated events;

机译：比例危害模型;考克斯模型时间相关协变量重复事件;

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专利

1. PRACTICAL APPROXIMATION FOR THE PROPORTIONAL HAZARD MODEL WITH TIME-DEPENDENT COVARIATES AND REPEATED EVENTS [J] . ALEXANDRA MENDES, NASSER FARD International Journal of Reliability, Quality and Safety Engineering . 2012,第6期

机译：具有时间依赖性协变量和重复事件的比例风险模型的实际逼近
2. ACCELERATED FAILURE TIME MODELS COMPARISON TO THE PROPORTIONAL HAZARD MODEL FOR TIME-DEPENDENT COVARIATES WITH RECURRING EVENTS [J] . ALEXANDRE C. MENDES, NASSER FARD International Journal of Reliability, Quality and Safety Engineering . 2014,第2期

机译：与具有递归事件的时变协变量比例风险模型的加速失效时间模型进行比较
3. Proportional hazards model for interval-censored failure times and time-dependent covariates: application to hazard of HIV infection of injecting drug users in prison. [J] . Seaman SR, Bird SM Statistics in medicine . 2001,第12期

机译：间隔检查失效时间和时间相关协变量的比例危害模型：在监狱中注射吸毒者对HIV感染危害的应用。
4. Proportional hazard model for time-dependent covariates with repeated events [C] . Alexandre Mendes, Nasser Fard ISSAT international conference on reliability quality in design . 2012

机译：重复事件的时间依赖协变量的比例危险模型
5. Assessing time-by-covariate interactions in Cox proportional hazards regression models using cubic spline functions. [D] . Hess, Kenneth Robert. 1992

机译：使用三次样条函数评估Cox比例风险回归模型中的逐变量交互作用。
6. MODELLING COUNTY LEVEL BREAST CANCER SURVIVAL DATA USING A COVARIATE-ADJUSTED FRAILTY PROPORTIONAL HAZARDS MODEL [O] . Haiming Zhou, Timothy Hanson, Alejandro Jara, -1

机译：使用协变量调整的脆弱性比例危害模型对县级乳腺癌生存数据进行建模
7. Marginal Distribution Plots for Proportional Hazards Models with Time-Dependent Covariates or Time-Varying Regression Coefficients [O] . Qiqing Yu, Junyi Dong, George Wong 2017

机译：具有时间依赖性协变量的比例危险模型的边缘分布图或时变回归系数

Proportional hazard model for time-dependent covariates with repeated events

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