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Toward complex multipolar selective neural stimulation

机译:朝向复杂的多极选择性神经刺激

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We introduce a new approach for the investigation of multipolar selective neural stimulation. We aim at comparing existing solutions from the literature and innovate in this field with advanced strategies. We have developed a multichannel stimulator, Stim'ND, which allows us to control independently the parameters of complex stimulation profiles of 12 channels for a large number of stimulating current configurations. In this paper, we present preliminary experimental results on a multi-contact cuff electrode, placed around the sciatic nerve of a rabbit 4 multipolar stimulation configurations have been tested and the achieved selectivity in terms of muscle activation investigated. The results are in accordance with the literature and enable us to validate our approach from theoretical and technological points of view. Furthermore the stimulator was designed following the norms and rules that apply to human active implantable medical device so that the technology is currently approved to be transferred to human trials.
机译:我们介绍了一种新方法,用于调查多极选择性神经刺激。我们的目标是将文献中的现有解决方案与先进的策略进行了比较了本领域的创新。我们开发了一个多通道刺激器,STIMNND,它允许我们独立地控制12个通道的复杂刺激轮廓的参数,用于大量刺激电流配置。在本文中,我们在围绕兔4个多极刺激配置的坐骨神经中呈现多触点箍电极上的初步实验结果已经过测试,并且在研究的肌肉激活方面取得的选择性。结果符合文献,使我们能够从理论和技术观点验证我们的方法。此外,刺激器遵循适用于人类活性可植入医疗设备的规范和规则,以便目前批准该技术被批准转移到人类试验。

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