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首页> 外文会议>IEEE International Conference on Nano/Micro Engineered and Molecular Systems >Large-scale Uniformly Hybrid Micro-nano Structure Wetting Solid Substrate for Surface-enhanced Raman Spectroscopy
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Large-scale Uniformly Hybrid Micro-nano Structure Wetting Solid Substrate for Surface-enhanced Raman Spectroscopy

机译：大型均匀杂化微纳米结构润湿固体基材，用于表面增强拉曼光谱

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摘要

Surface-enhanced Raman spectroscopy (SERS) is widely used in quantitative trace detection analysis fields benefit from its features of surface selectivity, fingerprint specificity, and rapidity without labeling. High sensitivity, reproducibility, analyte adsorption, and standardized preparation process are of critical importance to an ideal SERS solid substrate for detection applications in the actual circumstances. In this study, wafer-scale uniformly Si nanorods (SiNRs) arrays in conjunction with Au nanoparticles were fabricated as SERS solid substrate by polystyrene (PS) sphere self-assembly, nanosphere lithography and magnetron deposition techniques, which exhibited high sensitivity, reproducibility, and wettability. In detection of Rhodamine 6G (R6G) molecules, the SERS substrate reached an enhancement factor (EF) of 1010 and a limited detection of 5 ng/mL with a relative standard deviation (RSD) as low as 6.86% - 11.82%. The SERS substrates proposed in this work may serve as a promising detection scheme in chemical and biological fields.
机译：表面增强的拉曼光谱（SERS）广泛用于定量痕量检测分析领域，其具有表面选择性，指纹特异性和快速性的特征，而无需标记。高灵敏度，再现性，分析物吸附和标准化的制备方法对理想的SERS固体基材来说至关重要，以便在实际情况下进行检测应用。在该研究中，通过聚苯乙烯（PS）球体自组装，纳米光刻和磁控沉积技术，将晶片级均匀的Si纳米棒（SINR）阵列与Au纳米颗粒一起制造，纳米光刻光刻和磁控沉积技术。具有高灵敏度，再现性和润湿性。在检测罗丹明6G（R6G）分子中，SERS基板达到10的增强因子（EF） 10 并且有限地检测5ng / ml，相对标准偏差（RSD）低至6.86％-11.82％。本作工作中提出的SERS基材可以作为化学和生物领域的有希望的检测方案。

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