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首页> 外文会议>Society for Biomaterials annual meeting and exposition >Gellan gum based thiol-ene hydrogels with tunable properties for use as tissue engineering scaffold
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Gellan gum based thiol-ene hydrogels with tunable properties for use as tissue engineering scaffold

机译：基于Gellan Gum的硫醇 - 烯水凝胶，可调谐性能用作组织工程脚手架

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Conclusion: GG was modified by different amounts of methacrylate anhydride. Subsequent hydrogels were synthesized through chain growth, step growth and a mixture of both mechanisms. Hydrogels crosslinked by LMGG and chain growth HMGG exhibited a larger swelling ratio and were degradable by lysozyme while hydrogels made from HMGG through step growth and mixed model crosslinking methods were stable in lysozyme. Compression moduli were consistent among each type of hydrogel. In summary, hydrogel properties can be tuned through the different polymerization methods described here. Future work will focus on examining cell viability in the presence of the degradation products and further characterizing the mechanical properties of the gels by measuring G' and G" to reflect resistance to fracture.
机译：结论：GG通过不同量的甲基丙烯酸酐改性。通过链生长，步进生长和两种机制的混合物合成随后的水凝胶。通过LMGG和链增长HMGG交联的水凝胶表现出较大的溶胀比，并通过溶菌酶降解，同时通过步进生长和混合模型交联方法由HMGG制成的水凝胶在溶菌酶中稳定。压缩模量在每种类型的水凝胶中一致。总之，可以通过这里描述的不同聚合方法调节水凝胶性质。未来的工作将专注于在降解产物的存在下检查细胞活力，并通过测量G'和G“来反映抗骨折的抗性的凝胶的机械性能。

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