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Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded #hydrogels for inoculated cutaneous wound healing

机译：米诺环素在三重抗微生物加载的#Hydrogels中增强间充质基质/干细胞愈合表型，用于接种皮肤伤口愈合

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Conclusions: Minocycline induces a favorable change in MSC invasion capacity, proliferation, gene expression, ECM attachment, and VEGF secretion with subsequent increased angiogenesis. MSC, minocycline, vancomycin, and linezolid-loaded hydrogels decrease bacterial bioburden and accelerate healing in bacteria-inoculated wounds, demonstrating potential clinical viability for infection prophylaxis and advanced wound healing for full thickness cutaneous wounds.

机译：结论：米诺霉素诱导MSC侵袭能力，增殖，基因表达，ECM附着和VEGF分泌的有利变化，随后增加的血管生成。 MSC，米诺霉素，万古霉素和Libzolid加载水凝胶减少了细菌生物上并加速了细菌接种伤口中的愈合，展示了对全厚皮肤伤口的感染预防和晚期伤口愈合的潜在临床活力。

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《Society for Biomaterials annual meeting and exposition》|2017年|851 p.|共1页
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Alberto Daniel Guerra; Warren E Rose; Peiman Hematti; W. John Kao;
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1. Enhanced cutaneous wound healing by functional injectable thermo-sensitive chitosan-based hydrogel encapsulated human umbilical cord-mesenchymal stem cells [J] . Xu Hongjie, Huang Shanghui, Wang Jingjing, International Journal of Biological Macromolecules: Structure, Function and Interactions . 2019,第期

机译：通过功能可注射热敏壳聚糖的水凝胶增强皮肤伤口愈合包封的人脐带间充质干细胞
2. Mesenchymal stem cells/multipotent mesenchymal stromal cells (MSCs): Potential role in healing cutaneous chronic wounds [J] . ZouJ.-P., HuangS., PengY., The international journal of lower extremity wounds . 2012,第4期

机译：间充质干细胞/多能间充质基质细胞（MSCs）：在愈合皮肤慢性伤口中的潜在作用
3. Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes [J] . Marta H.G. Costa, Todd C. McDevitt, Joaquim M.S. Cabral, Journal of Biotechnology . 2017,第期

机译：人间充质茎/基质细胞的趋势配置，增强细胞旁静脉潜力对伤口愈合过程
4. Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded #hydrogels for inoculated cutaneous wound healing [C] . Alberto Daniel Guerra, Warren E Rose, Peiman Hematti, Society for Biomaterials annual meeting and exposition . 2017

机译：米诺环素增强三联抗菌药物＃水凝胶中的间充质基质/干细胞促愈合表型，以接种皮肤伤口愈合
5. Coencapsulation of Insulin-Producing Cells and Mesenchymal Stromal Cells in Pegda Hydrogels to Enhance Chronic Wound Healing [D] . Aijaz, Ayesha. 2017

机译：聚乙二醇水凝胶中胰岛素产生细胞和间质基质细胞的共包封，以增强慢性伤口愈合
6. Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded hydrogels [O] . Alberto Daniel Guerra, Warren E. Rose, Peiman Hematti, -1

机译：Minocycline增强三重加载抗生素的水凝胶中的间充质基质/干细胞促愈合表型
7. Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded hydrogels [O] . Alberto Daniel Guerra, Warren E. Rose, Peiman Hematti, 2017

机译：米诺环素在三重抗微生物加载水凝胶中增强间充质基质/干细胞愈合表型

Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded #hydrogels for inoculated cutaneous wound healing

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