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首页> 外文会议>International Conference on BioMedical Engineering and Informatics >The function coupling in young adults, old controls and old cognitively declined adults
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The function coupling in young adults, old controls and old cognitively declined adults

机译：年轻人的功能耦合，旧控件和旧的认知成年人

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This study explored the phase synchronization in young, old adults, and old cognitively declined adults using 2 minutes baseline resting EEG data. Sixteen young students recruited from shanghai university and eighteen elders recruited from a community in Shanghai, including nine old adults and nine old cognitively declined adults, participated in our experiment. The global phase synchrony index was calculated in each 1 second epoch and averaged for all EEG frequency band (delta, theta, alpha1, alpha2, beta, gamma1, gamma2). Then, we analyzed global phase synchronization, fronto-parietal functional coupling and frontal functional coupling at alpha2 band for three groups. The results revealed that old declined adults had decreased global phase synchronization at theta and alpha2 bands and lower frontal and fronto-parietal functional coupling at alpha2 band than old controls. Relative to young adults, the old controls had an active mechanism of compensation to maintain normal cognitive performance. In conclude the frontal and fronto-parietal functional coupling in alpha band may be helpful markers of cognitive decline associated with aging.
机译：本研究探讨在年轻的，年老的成年人的相位同步，并使用2个分钟之前的认知下降的成年人达到基线休息脑电图数据。十六青年学生毕业于上海大学招募的十八老人从社区招募在上海，包括九名老成人和九分老认知下降的成年人，参加我们的实验。全局相位同步指数在每次1秒时期计算并取平均值对于所有EEG频带（δ，θ，α1，α2，β，迦玛，GAMMA2）。然后，我们分析了全球相位同步，额顶叶功能耦合和额叶功能耦合在α-2频带三组。结果表明，老下降成年人已在theta和α-2频带降低全球相位同步，并在α-2比带老对照降低额叶和额顶叶功能耦合。相对于年轻人，老有控制的补偿作用机制，以维持正常的认知能力。在断定在α带额叶和额顶叶官能耦合可以是与老化相关的认知衰退有用标记。

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