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首页> 外文会议>Annual conference of the International Society of Exposure Science >Occupational Exposure and adverse health effects to Dermal Nicotine for Thai TraditionalTobacco Farmers in Nan Province, Northern Thailand
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Occupational Exposure and adverse health effects to Dermal Nicotine for Thai TraditionalTobacco Farmers in Nan Province, Northern Thailand

机译：泰国北部泰国泰国泰国传统机关农民皮肤尼古丁的职业暴露和不良健康影响

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Background: Thai Traditional Tobacco (Nicotiana Tabacum L.) as known as a non- Virginia type. A matured leaf contains more nicotine compare to Virginia type (3-4 times).In general process of tobacco production may lead to adverse health effect as Green Tobacco Sickness (GTS) Aims: To determine the prevalence of subjective health symptoms from occupational exposure with nicotine in Thai traditional tobacco production and to estimate potential risk factors associated with nicotine exposure from Thai traditional tobacco. Method: A cross- sectional study was conducted with 473 Thai traditional tobacco farmers in Praputtabath Sub-District and Phator Sub-District. The farmers were randomly selected and interviewed using face to face questionnaires. Results: Half of farmers were males (50.7%), the age of the famers were in the range of 20-65 years. During week period, the prevalence of subjective health symptoms from Thai traditional tobacco activities of headache and dizziness were 28.60% and 16.55%, respectively. The logistic regression analyses revealed that on the process, snapping off of tobacco leaves were associated with headache(OR6.875, 95%CI1.293-5.924) and dizziness(OR4.801, 95%CI0.077-0.867) and process of removing tobacco bud were associated with headache (OR10.775, 95%CI 1.644-7.167), dizziness (OR 8.195, 95%CI 1.505-8.890)and Nausea (OR5.497, 95%CI 1.400- 43.125). Additionally, during watering were independently associated with exposure to nicotine form wet tobacco leaves and wearing wet clothes (61%) (OR22.676, 95%CI 0.674 -0.848). During watering, the farmers exposured to wet leave and cloth about 6 hours per day and some of them reported on rash and/or irritate skin (29%). Conclusion: The study revealed that dermal pathway is a major route of exposure. Body soaking during watering may increase adverse health effects related to GTS. The health education program for increase awareness about health risk exposure of farmers is recommended.
机译：背景：泰国传统烟草（尼古利亚娜Tabacum L.）被称为非弗吉尼亚型。成熟的叶片含有与弗吉尼亚型（3-4次）比较的尼古丁。在烟草产量的一般过程中可能导致不利的健康效果，因为绿色烟草疾病（GTS）目标：确定主观健康症状与职业暴露的患病率尼古丁在泰国传统烟草生产中，估算泰国传统烟草尼古丁暴露的潜在风险因素。方法：在Praputabath次区和象域分区的473名泰国传统烟草农民进行了横断面研究。农民被随机选择并采访了面对面问卷。结果：一半的农民是男性（50.7％），着名的年龄在20-65岁的范围内。周期期间，泰国传统烟草的主观健康症状的患病率分别为28.60％和16.55％。 Logistic回归分析显示，在该过程中，烟草叶片捕捉与头痛（OR6.875,95％CI1.5.924）和头晕相关（OR4.801,95％CI0.07-0.867）和过程除去烟草芽用头痛（OR10.775，95％CI 1.644-7.167），头晕（OR 8.195，95％CI 1.505-8.890）和恶心（OR5.497，95％CI 1.400- 43.125）。另外，在浇水期间与暴露于尼古丁的湿烟叶和穿着湿衣服（61％）（OR22.676,95％CI 0.674 -0.848）外浇水。在浇水期间，农民暴露于湿休假和布，每天约6小时，其中一些人报告皮疹和/或刺激皮肤（29％）。结论：该研究表明，皮肤途径是暴露的主要途径。浇水期间的身体浸泡可能会增加与GTS相关的不良健康效果。建议提高对农民健康风险暴露的认识的健康教育计划。

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