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Traffic related air pollution and noise on cardiovascular outcomes: a systematic review

机译：交通相关的空气污染和噪声对心血管疾病的影响：系统评价

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Objective: This study financed by the National Collaborating Centre for Environmental Health aim of this review was to assess the confounding effect of one traffic-related exposure (noise or air pollutants) on the association between the other exposure and cardiovascular outcomes. Methods: A systematic review of English and French literature was conducted with the bibliographic databases Medlines and Embase. The confounding effects in studies were assessed by using the change in the point estimate with a cut-off point 10%. Results: The literature search yield 180 articles; 9 articles met our selection criteria. For most studies, the modification of the association between traffic-related noise or air pollutants vis-a-vis cardiovascular outcomes produced changes in point estimates lower than 10%. However, the results were inconsistent when assessing the effects on blood pressure, which may underlie the presence of a small confounding-effect. Conclusion: The results from this review suggest that important confounding of cardiovascular effects by traffic-related noise or reported air pollutants is unlikely. Studies with a standardized methodology and assessing the effects of specific traffic-related pollutants are needed to properly assess confounding effects.
机译：目的：这项由国家环境卫生合作中心资助的研究的目的是评估一种与交通有关的暴露（噪声或空气污染物）对另一种暴露与心血管结局之间的关联的混杂影响。方法：使用书目数据库Medlines和Embase对英语和法语文献进行系统的回顾。研究中的混杂效应是通过使用得分估计值的变化（截止点为10％）来评估的。结果：文献检索产生180篇文章; 9篇文章符合我们的选择标准。对于大多数研究而言，与交通相关的噪音或空气污染物与心血管疾病结局之间的关联性的改变产生的点估计值变化低于10％。但是，在评估对血压的影响时，结果不一致，这可能是由于存在小的混杂效应所致。结论：本次审查的结果表明，与交通相关的噪音或报告的空气污染物不会严重混淆心血管效应。需要使用标准化方法进行研究并评估特定交通相关污染物的影响，以正确评估混杂影响。

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