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Short-term effects of PM10 from Saharan dust on mortality in Southern Europe - Results of the MED-PARTICLES Project

机译:撒哈拉粉尘中的PM10对南欧死亡率的短期影响-MED-PARTICLES项目的结果

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Background. Enhanced short-term effects of particulate matter (PM) on mortality during desert dust outbreaks have been shown, with controversial results. Aim.To estimate the short-term effects of PM from Saharan dust on mortality in multiple Euro-Mediterranean cities, within the MED-PARTICLES project. Methods. Daily counts of cause-specific deaths were collected for 12 cities from Italy, Spain, Greece and France within 2001-2010. Data were available on daily mean concentrations of PM10 (PM<10 μm), PM2.5 (<2.5μm), PM2.5-10 (PM between 2.5 and 10 μm). Saharan dust episodes were identified using satellite data, operational models and back-trajectories. Daily PM10 concentrations attributable to Sahara were estimated from PM10 observations monitored at rural stations. PM10 from local sources was derived as the difference between total and Saharan PM10. City-specific Poisson regression models were fit, followed by random-effects meta-analysis. Results.The frequency of Saharan dust days ranged between 33% in Southern Greece and 13% in Northern Italy, with highest dust load in the Eastern Mediterranean basin (17 μg/m3 in Athens). Overall, all PM metrics were strongly associated with natural, cardiovascular and respiratory mortality, but no clear effect modification of Saharan dust outbreaks was detected, with high heterogeneity across cities. In contrast, on Saharan dust days, 10 μg/m3 increases in Saharan PM10, lag 0-5, were associated with 5.88% (95% confidence interval: 0.20,11.88) increased respiratory mortality, with no heterogeneity across cities,while no effect was found for PM10 from local sources (-0.42%; 95% CI: -8.14, 7.95) on Saharan days. Conclusions. We found evidence of effect modification of Saharan dust on PM10-mortality association only in a few cities. A strong homogeneous effect of PM10 from Sahara was found on respiratory mortality. On-going analyses deal to disentangle the effects of Saharan and local sources of PM10 and the heterogeneity of effects. Acknowledgements: MED-PARTICLES EU LIFE10 ENV/IT/327.
机译:背景。已显示出颗粒物(PM)对沙漠尘埃暴发期间死亡率的增强的短期影响,其结果颇具争议。目的:在MED-PARTICLES项目中,估算撒哈拉粉尘颗粒物对欧洲多个地中海城市死亡率的短期影响。方法。在2001-2010年期间,收集了意大利,西班牙,希腊和法国的12个城市的每日特定原因死亡计数。可获得有关PM10(PM <10μm),PM2.5(<2.5μm),PM2.5-10(PM在2.5至10μm之间)的日平均浓度的数据。撒哈拉尘埃事件使用卫星数据,运行模型和后向轨迹确定。撒哈拉沙漠地区每天的PM10浓度是根据农村站点监测的PM10观测值估算得出的。来自当地的PM10是总PM10与撒哈拉PM10之差。拟合特定城市的Poisson回归模型,然后进行随机效应荟萃分析。结果:撒哈拉尘埃的发生频率在希腊南部为33%,在意大利北部为13%,在地中海东部盆地最高(在雅典为17μg/ m3)。总体而言,所有PM指标均与自然死亡率,心血管疾病和呼吸道疾病死亡率密切相关,但未发现撒哈拉以尘暴爆发的明显效果得到改善,各城市之间存在高度异质性。相比之下,在撒哈拉沙尘天气,撒哈拉PM10浓度每升高10μg/ m3,滞后0-5,与呼吸道死亡率增加5.88%(95%置信区间:0.20,11.88)有关,各城市之间没有异质性,而没有影响在撒哈拉沙漠日发现了当地来源的PM10(-0.42%; 95%CI:-8.14,7.95)。结论我们仅在少数几个城市中发现了撒哈拉尘埃对PM10死亡率关联产生影响的证据。发现来自撒哈拉沙漠地区的PM10对呼吸系统死亡具有很强的均一作用。正在进行的分析旨在弄清撒哈拉沙漠和PM10的本地来源的影响以及影响的异质性。致谢:MED-PARTICLES EU LIFE10 ENV / IT / 327。

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