Microribbon-based Scaffolds Accelerate Bone Regeneration in a Cranial Defect Model

机译：基于微带的支架加速颅骨缺损模型中的骨再生。

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Here we report microribbon-based scaffolds as a novel platform to accelerate in vivo bone repair using in a critical sized, cranial defect model. In comparison with conventional hydrogels, the uRB-based scaffolds supported cell spreading, which may promote osteogenesis via mechanotransduction of cytoskeleton tension. Furthermore, the macroporosity of uRB-based scaffolds promoted cell proliferation, blood vessel ingrowth, and deposition of mineralized bone matrix. The platform reported herein may be particularly useful for repairing large defects of load-bearing tissues such as bone and cartilage.

机译：在这里，我们报告基于微带的支架作为一种新型平台，可在临界大小的颅骨缺损模型中使用，以加速体内骨骼修复。与常规水凝胶相比，基于uRB的支架支持细胞扩散，这可能通过细胞骨架张力的机械转导促进成骨作用。此外，基于uRB的支架的大孔性促进了细胞增殖，血管向内生长以及矿化的骨基质的沉积。本文报道的平台对于修复诸如骨骼和软骨的承重组织的大缺陷可能特别有用。

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《Society for Biomaterials annual meeting and exposition》|2014年|169-169|共1页
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Li-Hsin Han; Michael T. Chung; Bogi Conrad; Lorenzo Deveza; Xinyi Jiang; Michael T. Longaker; Fan Yang;
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1. Winner of the Young Investigator Award of the Society for Biomaterials at the 10th World Biomaterials Congress, May 17-22, 2016, Montreal QC, Canada: Microribbon-based hydrogels accelerate stem cell-based bone regeneration in a mouse critical-size cranial defect model [J] . Han Li-Hsin, Conrad Bogdan, Chung Michael T., Journal of biomedical materials research, Part A . 2016,第6期

机译：2016年5月17日至22日，加拿大蒙特利尔QC，在第十届世界生物材料大会上获得了生物材料学会年轻研究者奖：基于微带的水凝胶可在小鼠关键尺寸的颅骨缺损模型中促进基于干细胞的骨再生。
2. Winner of the Young Investigator Award of the Society for Biomaterials at the 10th World Biomaterials Congress, May 17-22, 2016, Montreal QC, Canada: Microribbon-based hydrogels accelerate stem cell-based bone regeneration in a mouse critical-size cranial defect model [J] . Han Li-Hsin, Conrad Bogdan, Chung Michael T., Journal of biomedical materials research, Part A . 2016,第6期

机译：2016年5月17日至22日，加拿大蒙特利尔QC，2016年5月17日至22日，蒙特利尔水凝胶中的蒙特利尔QC，蒙特利尔水凝胶在小鼠临界大小颅缺陷模型中加速干细胞基骨再生术语
3. Cranial Bone Defects Regeneration Using Platelet-Derived Growth Factor-BB-Loaded Chitosan/SBA-15 Composite Scaffold in a Rat Model [J] . Li Dianqi, Cheng Xin, Wan Qilong, Journal of biomaterials and tissue engineering . 2016,第7期

机译：在大鼠模型中使用血小板衍生的生长因子-BB负载的壳聚糖/ SBA-15复合支架的颅骨缺损再生。
4. Microribbon-based Scaffolds Accelerate Bone Regeneration in a Cranial Defect Model [C] . Li-Hsin Han, Michael T. Chung, Bogi Conrad, Society for Biomaterials annual meeting and exposition . 2014

机译：基于微微孔的支架在颅缺陷模型中加速骨再生
5. Healing of bone defects in a rodent calvarial defect model using strong porous bioactive glass (13-93) scaffolds [D] . Lin, Yinan. 2015

机译：使用坚固的多孔生物活性玻璃（13-93）支架修复啮齿动物颅骨缺损模型中的骨缺损
6. Microribbon-based hydrogels accelerate stem cell-based bone regeneration in a mouse critical-size cranial defect model [O] . Li-Hsin Han, Bogdan Conrad, Michael T. Chung, -1

机译：基于微带的水凝胶可在小鼠关键尺寸颅骨缺损模型中加速基于干细胞的骨再生
7. A computer-designed scaffold for bone regeneration within cranial defect using human dental pulp stem cells [O] . Doo Yeon Kwon, Jin Seon Kwon, Seung Hun Park, 2015

机译：使用人牙髓干细胞在颅骨缺陷内进行骨再生的计算机设计的支架

Microribbon-based Scaffolds Accelerate Bone Regeneration in a Cranial Defect Model

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