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Flow visualization for Nasal Cavity Flow in Aerosol Exhalation Through Nose Treatment

机译:通过鼻子处理气溶胶呼气的鼻腔流动的流动可视化

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Aerosol medicine exhalation through the nose (ETN) is one of promising and comprehensive treatment methods for Eosinophilic Chronic Rhinosinusitis (ECRS) with asthma. In this treatment, the patient inhales aerosol of inhaled corticosteroid (1CS) medicine from mouth using portable inhaler. Then a part of the aerosol still floats and remains in upper airway. When the patient exhales inhaled air through the nose, the aerosol is effectively transported on the walls of middle meatus and olfactory fissure. This study performed Computational Fluid Dynamics (CFD) analysis for the transport phenomena of aerosol medicine during exhalation period in order to evaluate the curative effect of ETN numerically. As a result of CFD analysis, ETN formed impinging flow toward upper wall of nasopharynx, subsequently complex swirl and circulation flow in the nasopharynx region. In addition, main flow of ETN passed upper region of nasal cavity. Such the tendencies affected on aerosol transport characteristics;;a part of aerosol particles moved into ethmoindal sinuses.
机译:气溶胶药物通过鼻子呼出(ETN)是具有哮喘嗜酸性慢性鼻窦炎(ECRS)的有前途和综合治疗方法之一。在这种处理中,患者使用便携式吸入器吸入吸入皮质类固醇(1CS)药物的气溶胶。然后是气溶胶的一部分仍然漂浮并留在上气道。当患者通过鼻子呼气吸入空气时,气溶胶在中间肉和嗅裂的墙壁上有效地运输。该研究对呼气时期的气溶胶药物运输现象进行了计算流体动力学(CFD)分析,以便在数值上评估ETN的疗效。作为CFD分析的结果,ETN形成朝向鼻咽的上壁的流动,随后在鼻咽区域中复杂的涡流和循环流动。此外,ETN的主流通过鼻腔的上部区域。这种对气溶胶运输特性影响的趋势;气溶胶颗粒的一部分进入乙型碱鼻窦。

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