The direct numerical simulation of a surface mounted cube in a channel flow at a Reynolds number of 5610 based on the cube height and bulk velocity was performed using the fifth-order compressible finite difference code OVERFLOW on overset chimera grids. Numerical simulation results are compared with and analyzed in light of published numerical and experimental results. The comparison of the time averaged results and turbulent statistics to previous DNS and experimental results validates the DNS procedure employed. Additionally, this analysis leads to recommendations on the settings of inlet and boundary conditions and the simulation domain to carry out a DNS that better conforms to the experimental conditions. An analysis of the turbulent quantities in the wake region indicates a break down of the isotropic turbulence assumption in high shear flows. The time averaged data revealed a system of six horseshoe vortices upstream of the cube, two counter-rotating vortices along the sides of the cube, and an arch-shaped vortex downstream of the cube.
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