Detection of mild Alzheimer's disease and mild cognitive impairment from elderly speech: Binary discrimination using logistic regression

机译：从老年人语音中检测轻度阿尔茨海默氏病和轻度认知障碍：使用逻辑回归的二元歧视

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In this research, we have developed a novel data-mining approach for detection of cognitive impairment, SPCIR (Speech Prosody-Based Cognitive Impairment Rating), which can discriminate between mild cognitive impairment and mild Alzheimer's disease from elderly using prosodic sign extracted from elderly speech during questionnaire test. This paper proposes a binary discrimination model of SPCIR using multivariate logistic regression and model selection using receiver operating characteristic (ROC) curve analysis, and reports the sensitivity and specificity of SPCIR for diagnosis (control; mild cognitive impairment/mild Alzheimer's disease).

机译：在这项研究中，我们开发了一种新的数据挖掘方法，用于检测认知障碍SPCIR（基于语音韵律的认知障碍评分），该方法可以使用老年人语音中的韵律符号来区分老年人的轻度认知障碍和轻度阿尔茨海默氏病在问卷测试中。本文提出了使用多元逻辑回归和接收者操作特征（ROC）曲线分析进行模型选择的SPCIR的二元判别模型，并报告了SPCIR对诊断（控制;轻度认知障碍/轻度阿尔茨海默氏病）的敏感性和特异性。

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《Annual International Conference of the IEEE Engineering in Medicine and Biology Society》|2015年|5569-5572|共4页
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Kato Shohei; Homma Akira; Sakuma Takuto; Nakamura Munehiro;
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diseases; geriatrics; medical disorders; neurophysiology; patient diagnosis; regression analysis; speech; ROC curve analysis; SPCIR sensitivity; SPCIR specificity; binary discrimination model; data-mining approach; elderly speech; mild Alzheimer disease detection; mild Alzheimer disease diagnosis; mild cognitive impairment detection; mild cognitive impairment diagnosis; multivariate logistic regression; prosodic sign extraction; receiver operating characteristic; speech prosody-based cognitive impairment rating; Dementia; Feature extraction; Senior citizens; Sensitivity; Speech;

机译：疾病;老年医学;医学疾病;神经生理学;患者诊断;回归分析;语音; ROC曲线分析; SPCIR敏感性; SPCIR特异性;二元歧视模型;数据挖掘方法;老年人讲话;轻度阿尔茨海默病检测;轻度阿尔茨海默病诊断;轻度认知障碍检测;轻度认知障碍诊断;多元logistic回归;韵律符号提取;接收者工作特征;基于语音韵律的认知障碍评分;痴呆;特征提取;老年人;敏感性;语音;

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1. 广场舞在轻度认知障碍伴抑郁症状社区老年人中的可行性研究 [J] . 姚秀钰, 赵禹, 尹敏, 国际护理科学（英文） . 2021,第004期
2. Easy Screening for Mild Alzheimer's Disease and Mild Cognitive Impairment from Elderly Speech [J] . Kato Shohei, Homma Akira, Sakuma Takuto Current Alzheimer research . 2018,第2期

机译：易于筛选轻度阿尔茨海默病和老年人演讲的轻度认知障碍
3. Combinations of Multiple Neuroimaging Markers using Logistic Regression for Auxiliary Diagnosis of Alzheimer Disease and Mild Cognitive Impairment [J] . Mao Nini, Liu Yunting, Chen Kewei, Neuro-degenerative diseases . 2018,第2a3期

机译：使用逻辑回归对阿尔茨米尔病的辅助诊断和轻度认知障碍的逻辑回归组合
4. Cognitive and Functional Profiles in Mild-to-Moderate Alzheimer’s Disease and Mild Cognitive Impairment Compared to Healthy Elderly [J] . Mark Marsico, Celeste A. de Jager, April Grant, Advances in Alzheimer's Disease . 2014,第4期

机译：与健康老年人相比，轻度至中度阿尔茨海默氏病和轻度认知障碍的认知和功能特征
5. Detection of Mild Alzheimer's Disease and Mild Cognitive Impairment from Elderly Speech: binary discrimination using logistic regression [C] . Shohei Kato, Akira Homma, Takuto Sakuma, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2015

机译：检测轻度阿尔茨海默氏病和老年人语言的轻度认知障碍：使用Logistic回归的二进制鉴别
6. Selective attention in normal elderly, amnestic mild cognitive impairment, and early Alzheimer's disease: Evaluation of psychometric tests of frontal function and saccadic eye movements. [D] . Hemraj, Alisha. 2006

机译：正常老年人，轻度遗忘性轻度认知障碍和早期阿尔茨海默氏病的选择性注意：对额叶功能和眼跳运动的心理测验的评估。
7. Cognitive and Structural Correlates of Conversational Speech Timing in Mild Cognitive Impairment and Mild-to-Moderate Alzheimer’s Disease: Relevance for Early Detection Approaches [O] . Céline De Looze, Amir Dehsarvi, Lisa Crosby, 2021

机译：轻度认知障碍和温和至中等阿尔茨海默病中会话语音时序的认知和结构性相关性：早期检测方法的相关性
8. P1-312: Differentiating amnestic mild cognitive impairment converting to probable Alzheimer's disease from stable amnestic mild cognitive impairment using FDG-PET and an Alzheimer's disease-related hypometabolism overlap index [O] . Napatkamon Ayutyanont, Kewei Chen, Xiaofen Liu, 2008

机译：P1-312：使用FDG-PET和Alzheimer相关的低次抑制障碍与稳定的Amnestic认知障碍相差，将Amnestic MILD认知障碍与Alzheimer相关的低次抑制重叠指数相差

Detection of mild Alzheimer's disease and mild cognitive impairment from elderly speech: Binary discrimination using logistic regression

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