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首页> 外文会议>Annual International Conference of the IEEE Engineering in Medicine and Biology Society >Heart rate variability in cyclic alternating pattern during sleep in healthy and Nocturnal Front Lobe Epilepsy patients
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Heart rate variability in cyclic alternating pattern during sleep in healthy and Nocturnal Front Lobe Epilepsy patients

机译：健康和夜间前额叶癫痫患者睡眠中周期性交替模式的心率变异性

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The aim of this paper is to assess heart rate variability (HRV) during the cyclic alternating pattern, which is a sleep phenomenon, composed by cortical events that interrupt the basal oscillation of the NREM sleep stage. These cortical events are called A-phases and classified into three subtypes: A1, A2, A3. In addition, a comparison between healthy and Nocturnal Front Lobe Epilepsy (NFLE) patients was carried out. HRV was assessed by means of a time-varying autoregressive (TVAR) model with an adaptive filtering prediction scheme and by the time-varying square root of the mean of the sum of the squares of differences (RMSSD) of the RR intervals. For each A-phase, two signal segments were evaluated, the first one before the onset of the A-phase and the second one after the onset of the A-phase. An increase in the sympathetic outflow was suggested by higher values of low-frequency (LF) power in the three A-phases after the onset of A-phases, where A3-phases showed the largest changes. Increases in LF power were related with increases in heart rate in the same signal segments. These differences were found in both healthy and NFLE patients. LF/HF ratio and normalized LF power in A1-phases resulted significantly higher in NFLE patients in comparison with healthy subjects, which could suggest that there is a shift in the sympatho-vagal balance towards a more sympathetically mediated control of heart rate involving A1-phases in NFLE patients.
机译：本文的目的是评估周期性交替模式下的心率变异性（HRV），这是一种睡眠现象，由皮质事件中断NREM睡眠阶段的基础振荡组成。这些皮质事件称为A期，分为三个亚型：A1，A2，A3。此外，还对健康人和夜间前叶癫痫（NFLE）患者进行了比较。通过具有自适应滤波预测方案的时变自回归（TVAR）模型以及RR间隔的差平方和（RMSSD）的均值的时变平方根来评估HRV。对于每个A相，评估了两个信号段，第一个信号段在A相开始之前，第二个信号段在A相开始之后。 A相开始后三个A相的低频（LF）功率值越高，表明交感神经流出的增加，其中A3相显示出最大的变化。在相同信号段中，LF功率的增加与心率的增加有关。在健康和NFLE患者中均发现了这些差异。与健康受试者相比，NFLE患者的A1期LF / HF比和归一化LF功率显着更高，这表明交感迷走神经平衡已朝着由交感神经介导的对A1的心律控制进行了转移NFLE患者的分期。

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