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首页> 外文会议>Australasian Fluid Mechanics Society;Australasian fluid mechanics conference >Experimental Investigation of Airway Pressures in Human Airway Models with Compliant Components
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Experimental Investigation of Airway Pressures in Human Airway Models with Compliant Components

机译：兼容组件的人体气道模型中气道压力的实验研究

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A new manufacturing process to construct a human airway modelwith key complaint components was developed. Experimentalanalysis was then performed with the results compared to that of arigid model to investigate the influence that soft tissues had onairway pressures during natural and nasal high flow therapy(NHFT) assisted breathing and investigate the validity of previousrigid wall assumptions in experimental investigation. The airwaygeometry was obtained from CT scan data and 3D printingtechnology was used to fabricate the anatomically correct polymermodel. A soft silicone was used to simulate the compliance of thetongue, soft palate and vocal fold regions. Breathing wassimulated in both the rigid and compliant model using a computercontrolled pulsatile pump. The results revealed that the compliantairway model experienced different static pressures during bothnatural and NHFT assisted breathing. Natural breathing resultsshowed similar oscillatory pressure profiles between compliantand rigid airways, however the compliant airway had largerpressures on peak expiration and lower pressures on peakinspiration at the velopharynx and oropharynx regions. With theapplication of NHFT at 30 L/min, the compliant airway had greaterpressures than the rigid airway for both breathing phases, upstreamof the site of compliance. Below the soft palate, only peakexpiratory pressures were affected. At NHFT at 60 L/min, thecompliant airway pressures were greater than their correspondingrigid pressures for both breathing phases, at all regions.
机译：建立人气道模型的新制造工艺 与主要投诉组件的开发。实验性 然后进行分析，结果与 刚性模型来研究软组织对软组织的影响 自然和鼻高流量治疗期间的气道压力 （NHFT）辅助呼吸并调查先前的有效性 实验研究中的刚性墙假设。气道 从CT扫描数据和3D打印获得几何形状 技术被用来制造解剖学上正确的聚合物 模型。使用柔软的硅树脂来模拟 舌，软soft和声带区域。呼吸原为 使用计算机在刚性和柔性模型中进行仿真 控制脉动泵。结果显示，符合标准 气道模型在两个过程中都经历了不同的静压 自然和NHFT辅助呼吸。自然呼吸的结果 在顺应性之间显示相似的振荡压力曲线 和刚性气道，但是顺应性气道更大 峰值到期时的压力和峰值较低的压力 velopharynx和口咽区域的灵感。随着 以30 L / min的速度应用NHFT，顺应性气道具有更大的 上游两个呼吸阶段的压力均大于刚性气道的压力 合规地点。在软pa下，仅峰 呼气压力受到影响。在NHFT下以60 L / min的速度 顺应性气道压力大于相应的气道压力 在所有区域，两个呼吸阶段的压力都很大。

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