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首页> 外文会议>Annual conference of the International Society of Exposure Science >Concordance, transparency, and access: Why do we need these in exposure science and health outcome research?
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Concordance, transparency, and access: Why do we need these in exposure science and health outcome research?

机译：一致性，透明度和可及性：为什么在接触科学和健康结果研究中需要这些？

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In observational research, evidence is usually derived from multiple studies, and any single result is rarely considered sufficient for public health decision making. Despite more than five decades of research and thousands of studies published, the ability to draw robust conclusions regarding the presence or absence of causal links between specific environmental exposures and human health remains limited. To develop policies that are protective of public health and can withstand scrutiny, agencies need to rely on investigations of satisfactory quality that follow sufficiently concordant protocols in terms of exposure assessment, outcome ascertainment, data analysis, and reporting of results. Absent such concordance, the ability of environmental epidemiology studies to inform decision making is greatly diminished. Systems and tools are proposed here to improve concordance among environmental epidemiology studies. Specifically, working systems in place in other fields of research are critically examined and used as guidelines to develop analogous policies and procedures for environmental epidemiology. A three-part path forward (Figure 1) toward more concordant, transparent, and readily accessible environmental epidemiology evidence that parallels ongoing efforts in medical research is described. The three parts address methods for improving quality and accessibility of systematic reviews, access to information on ongoing and completed studies, and principles for reporting. The goals are to increase the value of epidemiological research in public health decision making.
机译：在观察性研究中，证据通常来自多项研究，很少有任何单一结果被认为足以进行公共卫生决策。尽管进行了超过五十年的研究并且发表了数千项研究，但就特定环境暴露与人类健康之间是否存在因果关系得出结论的能力仍然有限。为了制定保护公众健康并能经受审查的政策，各机构需要依靠对质量的满意调查，这些调查应在暴露评估，结果确定，数据分析和结果报告方面遵循足够一致的方案。如果没有这样的一致性，环境流行病学研究提供决策依据的能力就会大大降低。本文提出了系统和工具，以提高环境流行病学研究之间的一致性。具体而言，对其他研究领域中建立的工作系统进行了严格审查，并将其用作制定类似的环境流行病学政策和程序的指南。描述了朝着更加一致，透明和易于访问的环境流行病学证据前进的三部分（图1），该证据与医学研究中正在进行的努力相平行。这三个部分讨论了提高系统评价的质量和可及性，获取正在进行的和已完成的研究的信息以及报告原则的方法。目标是增加流行病学研究在公共卫生决策中的价值。

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