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5 years of flushing out drug use with sewage-based epidemiology

机译:基于污水流行病学的5年冲洗毒品使用

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A collaborative study on the analysis of wastewater for estimating the use of illicit drugs has been performed between 2011 and 2015 allowing spatial differences and temporal changes in illicit drug use to be performed in a large population (i.e. between 11.5-24.7 million people in up to 42 cities; www.score-cost.eu). The study was performed according to best practice where the sewer networks and sampling systems were characterized by the use of a questionnaire and analytical performance by means of repeated interlaboratory test studies. The questionnaire highlighted where differences in sewer design and sampling protocols may influence the data, while the interlaboratory tests showed that the analytical data could be safely compared. In 2011 the approach was simultaneously applied in 19 European cities, making it possible to directly compare illicit drug loads over a 1-week period. The main findings from 2011 were distinct spatial patterns in drug use across Europe. Cocaine use was higher in Western and Central Europe and lower in Northern and Eastern Europe. The total consumption for Europe as a whole is extrapolated to 356 kg daily, which would account for approximately 10 - 15 % of the global supply of cocaine (as estimated by the United Nations Office on Drugs and Crime). High per capita ecstasy loads were measured in Dutch cities, as well as in Antwerp and London. Cocaine and ecstasy loads were significantly elevated during the weekend compared to weekdays. As the collaborative network developed over 70 different cities, including a number from North America and Australia, many of these have been tested within this collaboration over a number of years. Increased spatial coverage has allowed a more robust comparison with surveillance data, which generally were in good agreement. Temporal differences show relatively stable loads overall for all of the investigated drugs across Europe. Wastewater analysis on the above scale has allowed the large spatial and temporal coverage of illicit drug use. This has been achieved quickly and cheaply and highlights the unique data that wastewater provides on illicit drug use that can be used for comparisons with surveillance data or used to plug gaps in available data. Wastewater analysis offers clear benefits when used alongside existing surveillance methods and we recommend its implementation on a formal basis.
机译:2011年至2015年间,开展了一项针对废水分析的合作研究,以评估非法药物的使用,从而可以在大量人口中(即,多达11.5到2470万人之间)对非法药物的使用进行空间差异和时间变化。 42个城市; www.score-cost.eu)。该研究是根据最佳实践进行的,在该实践中,下水道网络和采样系统的特点是使用问卷调查表和通过重复的实验室间测试研究进行分析的性能。问卷突出显示了下水道设计和采样方案的差异可能会影响数据,而实验室间测试表明可以安全地比较分析数据。 2011年,该方法同时在19个欧洲城市中应用,这使得可以在1周的时间内直接比较非法药物的使用量。 2011年的主要发现是整个欧洲毒品使用的不同空间格局。西欧和中欧的可卡因使用量较高,北欧和东欧的可卡因使用量较低。整个欧洲的总消费量据推测为每日356公斤,约占全球可卡因供应量的10-15%(据联合国毒品和犯罪问题办公室估计)。在荷兰城市以及安特卫普和伦敦,人均摇头丸负荷很高。与工作日相比,周末可卡因和摇头丸的负荷量明显增加。随着协作网络在70多个不同城市(包括北美和澳大利亚的多个城市)中发展,许多年来已经在此协作中进行了测试。空间覆盖率的提高使监视数据与监视数据的比较更加稳健,而监视数据通常是一致的。时间差异显示整个欧洲所有被调查药物的总体负荷相对稳定。规模以上的废水分析使非法毒品的使用在空间和时间上得到了很大的覆盖。这已经迅速而廉价地实现了,并突出了废水提供的关于非法药物使用的独特数据,可用于与监测数据进行比较或用于弥补现有数据中的空白。与现有的监测方法一起使用时,废水分析具有明显的好处,我们建议在正式的基础上进行废水分析。

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