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Small area, low power neural recording integrated circuit in 130 nm CMOS technology for small mammalians

机译:适用于小型哺乳动物的采用130 nm CMOS技术的小面积,低功耗神经记录集成电路

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In neuroscience research the development of the brain and the treatment of diseases like certain forms of epilepsy is analysed with genetic mouse disease models. For the special case of the recording from neonatal mice a custom designed integrated circuit is presented. Neonatal mice are only two to three centimetres large and have a weight of only a few gram. Thus, the recording circuitry has to be very small and light weight. The integrated circuit implements 16 low-area, low-power analogue differential preamplifiers with a bandpass characteristic (0.5 Hz to 10 kHz). A multiplexed structure of 8:1 multiplexer, post amplifier and 10 bit successive approximation register (SAR) analogue-to-digital converter (ADC) digitizes the signals with high resolution. The digital data is transmitted via a Serial Peripheral Interface (SPI). The integrated circuit has been implemented in a 130 nm CMOS technology and has been successfully applied in in-vivo measurements with an adult mouse.
机译:在神经科学研究中,使用遗传小鼠疾病模型分析了大脑的发育和某些疾病(如某些形式的癫痫病)的治疗。对于新生小鼠记录的特殊情况,提出了一种定制设计的集成电路。新生小鼠只有两到三厘米大,体重只有几克。因此,记录电路必须非常小且重量轻。该集成电路实现了具有带通特性(0.5 Hz至10 kHz)的16个低区域,低功率模拟差分前置放大器。 8:1多路复用器,后置放大器和10位逐次逼近寄存器(SAR)模数转换器(ADC)的多路复用结构将高分辨率的信号数字化。数字数据通过串行外围接口(SPI)传输。该集成电路已采用130 nm CMOS技术实现,并已成功应用于成年小鼠的体内测量中。

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