首页> 外文会议>International astronautical congress >THE ENHANCED ANTIBACTERIAL POTENCY OF THE ACTIVE COMPOUNDS FOUND IN TURMERIC AND NEEM IN THE PRESENCE OF SUNLIGHT
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THE ENHANCED ANTIBACTERIAL POTENCY OF THE ACTIVE COMPOUNDS FOUND IN TURMERIC AND NEEM IN THE PRESENCE OF SUNLIGHT

机译:存在阳光下,在二甲双胍和神经元中发现的活性化合物的抗菌活性增强

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Objective: The induced inactivation of S.aureus, S.typhi and K.pneumoniae by turmeric and neem extracts, curcumin and nimbidin respectively, in the presence of sunlight. Design and methods: Turmeric possesses a number of health benefits which include; its antibacterial benefit (working on both gram positive and gram negative bacteria) , it is a good source of antioxidants ,it acts as a potent anti-inflammatory agent, antifugal activity, antiproliferative and importantly it also contains anticancer propcrtics(3,4). Neem also possesses both gram positive and gram negative antibacterial properties. Apart from its antibacterial property neem also contains antifungal, antimalarial, antiulcerogenic, antifertility properties, it can treat some forms of sexually transmitted diseases such as gonorrhea, syphilis, chlamydia, genital herpes, genital/vaginal warts, candidacies, and urinary tract infections (1). Sunlight serves as a mutagen, in which the non-ionized radiation (electromagnetic radiation) from the sun's UV light causes alterations in bacterial DNA structure (2). This alteration of the DNA may lead to inability to repair, lack of replication and hindrance in the development of resistance mechanisms (2). The mutagenic effect of the sun's UV radiation combined with the antibacterial effect, of both turmeric and neem may pose as an effective antibacterial treatment. Samples of bacteria to be used were cultured over a 48 hour period in nutrient agar. Afterwards, the cultured bacteria were inoculated into the blood samples that were stored in anticoagulant test tubes and left for a further 24 hours. The infected blood samples untreated and treated with turmeric and neem were then placed in conditions of darkness and sunlight for a 2 hour period. The process of non-ionized radiation (solar irradiation) was done during the midday period (from 12-2 pm) to make adequate use of the sun's energy. Following that 2 hour period the samples were then tested and results were analysed.
机译:目的:在阳光下,姜黄和印em提取物,姜黄素和宁比丁分别诱导金黄色葡萄球菌,鼠伤寒沙门氏菌和肺炎克雷伯菌的失活。设计和方法:姜黄具有许多健康益处,包括:它具有抗菌作用(对革兰氏阳性菌和革兰氏阴性菌都有作用),是抗氧化剂的良好来源,可作为有效的消炎剂,抗真菌活性,抗增殖剂,并且重要的是它还含有抗癌作用(3,4)。印em还具有革兰氏阳性和革兰氏阴性抗菌特性。印em除具有抗菌特性外,还具有抗真菌,抗疟疾,抗溃疡,抗生育的特性,还可以治疗某些形式的性传播疾病,例如淋病,梅毒,衣原体,生殖器疱疹,生殖器/阴道疣,念珠菌和尿路感染(1)。 )。阳光是一种诱变剂,来自太阳紫外线的非电离辐射(电磁辐射)会引起细菌DNA结构的改变(2)。 DNA的这种改变可能导致无法修复,缺乏复制以及抗药性机制的发展受阻(2)。太阳的紫外线辐射的诱变作用与姜黄和印the的抗菌作用相结合,可构成一种有效的抗菌治疗方法。将要使用的细菌样品在营养琼脂中培养48小时。之后,将培养的细菌接种到血液样本中,然后将其存储在抗凝试管中并放置24小时。然后将未经处理和用姜黄和印em处理过的感染血样置于黑暗和阳光下2小时。非电离辐射(太阳辐射)的过程在中午(从下午12点至下午2点)进行,以充分利用太阳的能量。在2小时之后,然后测试样品并分析结果。

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