Image Based Automated ASPECT Score for Acute Ischemic Stroke Patients

机译：基于图像的急性缺血性卒中患者的自动ASPECT评分

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The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is a tool to assess early ischemic changes in acute stroke patients and found to be superior when applied to contrast-based image modalities. We hypothesized that automated ASPECTS scores have no differences with the manual scoring. We generated time-invariant CTA (tiCTA) from CT Perfusion dataset and measured the ASPECTS score automatically and manually. Statistical analysis was performed to see the differences. The association of both measurements with patient outcome was measured using NIH stroke scale at admission, final infarct size, and 3-month modified Rank Scale (mRS) determined using the Spearman correlation coefficient. As a result, the difference between automated and manual ASPECT scores was statistically not significant (p=0.18). Both automated ASPECTS scores were identical in 40% of the patients for the total score. While all ASPECTS scores have limited association with outcome, our study illustrates the usability of automated ASPECTS applied on tiCTA, allowing simplification of CT workflow for acute ischemic stroke patients and promoting faster analysis.

机译：艾伯塔省卒中计划早期计算机断层扫描评分（ASPECTS）是一种评估急性卒中患者早期缺血性变化的工具，当将其应用于基于对比的图像方式时，其优越性。我们假设自动ASPECTS评分与手动评分没有差异。我们从CT灌注数据集生成了时不变CTA（tiCTA），并自动和手动测量了ASPECTS得分。进行统计分析以查看差异。使用入院时的NIH卒中量表，最终的梗塞面积和使用Spearman相关系数确定的3个月修正等级量表（mRS）来测量这两种测量结果与患者预后的关联。结果，自动和手动ASPECT评分之间的差异在统计学上不显着（p = 0.18）。在总分数中，有40％的患者的两个自动ASPECTS分数相同。尽管所有ASPECTS评分与结局之间的联系有限，但我们的研究表明，将自动ASPECTS应用于tiCTA的可用性，可以简化急性缺血性中风患者的CT工作流程并促进更快的分析。

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《International Conference on Instrumentation, Communications, Information Technology, and Biomedical Engineering》|2017年|1-5|共5页
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Fahmi Fahmi; Henk A. Marquering; Charles B. Majoie; Marianne A. van Walderveen; Geert J. Streekstra; Ed vanBavel;
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Manuals; Computed tomography; Observers; Biomedical engineering; Biomedical imaging; Instruments;

机译：手册;计算机断层扫描;观察员;生物医学工程;生物医学成像;仪器;

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1. The clot burden score, the Boston Acute Stroke Imaging Scale, the cerebral blood volume ASPECTS, and two novel imaging parameters in the prediction of clinical outcome of ischemic stroke patients receiving intravenous thrombolytic therapy [J] . Niko Sillanpaa, Jukka T. Saarinen, Harri Rusanen, Neuroradiology . 2012,第7期

机译：血栓负荷评分，波士顿急性中风影像量表，脑血容量ASPECTS和两个新的影像学参数可预测接受静脉内溶栓治疗的缺血性中风患者的临床结局
2. The clot burden score, the Boston Acute Stroke Imaging Scale, the cerebral blood volume ASPECTS, and two novel imaging parameters in the prediction of clinical outcome of ischemic stroke patients receiving intravenous thrombolytic therapy [J] . SillanpaaN., SaarinenJ.T., RusanenH., Neuroradiology . 2012,第7期

机译：血栓负荷评分，波士顿急性中风影像量表，脑血容量ASPECTS以及两个新的影像学参数可预测接受静脉内溶栓治疗的缺血性中风患者的临床结局
3. e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients [J] . Nagel Simon, Sinha Devesh, Day Diana, International journal of stroke: official journal of the International Stroke Society . 2017,第6期

机译：E-Apposs软件对神经加理学家的非较低者，在急性缺血性脑卒中患者的计算机断层扫描扫描应用方面
4. Image Based Automated ASPECT Score for Acute Ischemic Stroke Patients [C] . Fahmi Fahmi, Henk A. Marquering, Charles B. Majoie, International Conference on Instrumentation, Communications, Information Technology, and Biomedical Engineering . 2017

机译：基于图像的急性缺血性卒中患者的自动化方面分数
5. An analysis of the relationship between hyperglycemia and the National Institute of Health Stroke Scale (NIHSS) scores in ischemic stroke patients. [D] . Bohl, Susan. 2010

机译：高血糖与缺血性中风患者国立卫生研究院卒中量表（NIHSS）评分之间的关系分析。
6. Use of Diffusion‐Weighted Imaging‐Alberta Stroke Program Early Computed Tomography Score (DWI‐ASPECTS) and Ischemic Core Volume to Determine the Malignant Profile in Acute Stroke [O] . Takeshi Yoshimoto, Manabu Inoue, Hiroshi Yamagami, 2019

机译：使用弥散加权成像-艾伯塔中风计划早期计算机断层扫描评分（DWI-ASPECTS）和缺血核心体积来确定急性中风的恶性程度
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Image Based Automated ASPECT Score for Acute Ischemic Stroke Patients

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