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A 3600 × 3600 large-scale ISFET sensor array for high-throughput pH sensing

机译:用于高通量pH传感的3600×3600大规模ISFET传感器阵列

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This paper presents a large-scale ion-sensitive field effect transistor (ISFET) array chip for pH sensing. A 3600 × 3600-pixel ISFET sensor array and corresponding readout circuitry are designed and fabricated using a conventional 0.18-μm CMOS process flow. High-throughput pH sensing is achieved with real-time data acquisition of 26 frame per second. A pH sensitivity of 73.56 mV/pH is achieved owing to the in-pixel amplification. This high-density, CMOS compatible and cost efficient ISFET array chip has great potential to be used in applications such as semiconductor DNA detection and sequencing.
机译:本文提出了一种用于pH传感的大规模离子敏感场效应晶体管(ISFET)阵列芯片。使用常规的0.18μmCMOS工艺流程设计和制造3600×3600像素ISFET传感器阵列和相应的读出电路。通过每秒26帧的实时数据采集可实现高通量pH传感。由于像素内放大,因此可实现73.56 mV / pH的pH灵敏度。这种高密度,兼容CMOS且具有成本效益的ISFET阵列芯片具有巨大的潜力,可用于诸如半导体DNA检测和测序之类的应用中。

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