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Electrochemical Corrosion and Invitro Biocompatibility of Polypyrrole/Pectin Composites coatings on 316L SS Implants

机译:聚吡咯/果胶复合材料涂层在316L SS植入物上的电化学腐蚀和体外生物相容性

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Combination of a natural biodegradable polymer with a synthetic polymer delivers admirable capability in advanced biomedical materials. For this purpose, biodegradable conductive composites based on polypyrrole/Pectin will be synthesized by in situ electrochemical polymerization of pyrrole in the presence of Pectin in oxalic acid medium Raman and UV-Vis spectroscopy will be used to characterize the synthesized bio-composites. Raman spectrum will be employed to find the interaction between the π-conjugated structure of PPy and the Pectin units in the investigated composite. SEM results reveal the influence of the Pectin inclusion on polypyrrole surface morphology. Electrochemical corrosion behavior of the coated implant alloys in simulated body fluid (SBF) medium will be examined using potentiodynamic polarization and electrochemical impedance spectroscopic measurements. Further, in vitro cell culture studies will also be carried out using MG-63 human osteoblast cells to estimate the biocompatibility of PPy/Pectin composite coatings. Significant enhancements in surface protective and biocompatibility performance will be expected and it will suggest possible application as a bioactive coating material on 316L SS implants for biomedical fields.
机译:天然可生物降解的聚合物与合成聚合物的结合为先进的生物医学材料提供了令人赞叹的功能。为此,将在草酸介质拉曼中在果胶存在下通过吡咯的原位电化学聚合来合成基于聚吡咯/果胶的可生物降解导电复合材料,并将使用紫外-可见光谱法表征合成的生物复合材料。拉曼光谱将用于发现所研究复合物中PPy的π共轭结构与果胶单元之间的相互作用。 SEM结果揭示了果胶包合物对聚吡咯表面形态的影响。将使用电位动力学极化和电化学阻抗谱测量来检查涂覆的植入物合金在模拟体液(SBF)介质中的电化学腐蚀行为。此外,还将使用MG-63人成骨细胞进行体外细胞培养研究,以评估PPy /果胶复合涂层的生物相容性。预期表面保护和生物相容性性能将显着提高,这将有望作为生物活性涂层材料在316L SS植入物上用于生物医学领域。

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