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Evaluation of Piezoresistive Polymer-based Traces for Non-invasive Sensor Patch

机译：基于压阻聚合物的无痕传感器贴片痕迹评估

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In this paper, we shall discuss the suitable alternative material to gold for creating traces or electrodes of a noninvasive flexible sensor patch that is used for detecting early extravasation during intravenous cannulation. The samples were prepared by printing 5 μm- to 10 μm-thin piezoresistive polymer-based Carbon paste on a base polymer patch, also called the adhesive film. The first samples have the traces embedded in between two base adhesive films. The sensitivity of the samples was characterized by using a pressure chamber/jig with 4 cm hole to mimic an extravasation by bump formation when pumped with compressed dry air (CDA) that is connected to a 15 psi source. The sensitivity value obtained was 20% up to 23% at 0.16 psi. After optimization of the curing temperature of the adhesive film and piezoresistive polymer-based Carbon traces, ex-vivo test was conducted with the prototype sample placed on the cannulation site of a pork front hock. At 2 ml and 5 ml infused fluid, the sensitivity obtained is only 1.1% and 2.44%, respectively. The overall prototype dimension of all samples is 6 × 7 cm2. The second samples were prepared with narrower trace width and spacing than the first samples. Sensitivity obtained from the second sample at 0.16 psi increased to 50% up to 79%. The third samples were prepared with the same narrow trace with as the second sample, but this time the piezoresistive polymer-based traces were not embedded in two adhesive films, making the sample a single layer patch only. Sensitivity obtained at 0.16 psi increased further to 140% up to 200%. The 0.16 psi readout is based on previous data that at this pressure induced in the 4 mm hole where the adhesive film is placed over, it translates to 3 mm bump height at 2 ml infused volume on the skin. The results suggest a strong potential in the development of the piezoresistive polymer-based Carbon traces for flexible non-invasive sensor patch for early extravasation detection.
机译：在本文中，我们将讨论合适的替代金的材料，以创建无创柔性传感器贴片的痕迹或电极，该贴片可用于检测静脉插管过程中的早期渗出。通过在基础聚合物贴片（也称为粘合膜）上印刷5μm至10μm薄的压阻聚合物基碳糊来制备样品。第一个样品的痕迹嵌入两个基础胶粘剂膜之间。样品的敏感性是通过使用带有4 cm孔的压力室/夹具来模拟的，当泵送与15 psi压力源相连的压缩干燥空气（CDA）时，会由于隆起的形成而产生溢出现象。在0.16 psi下获得的灵敏度值为20％至23％。优化粘合膜的固化温度和基于压阻聚合物的碳迹线后，将原型样品放置在猪肉前飞叉的插管部位进行离体测试。在注入2 ml和5 ml的液体时，获得的灵敏度分别仅为1.1％和2.44％。所有样品的总体原型尺寸为6×7厘米 2 。制备的第二个样品的迹线宽度和间距比第一个样品窄。在0.16 psi下从第二个样品获得的灵敏度增加到50％，最高达到79％。用与第二个样品相同的窄走线制备了第三个样品，但是这次压敏聚合物基走线未嵌入两个粘合膜中，从而使该样品仅是单层贴剂。在0.16 psi下获得的灵敏度进一步提高到140％，最高达到200％。 0.16 psi读数基于先前的数据，即在放置粘合剂膜的4 mm孔中在此压力下感应产生的压力，在注入2 ml皮肤上的情况下，它转换为3 mm的凸起高度。结果表明，在用于早期外渗检测的柔性非侵入性传感器贴片的压阻聚合物基碳迹线的开发中，具有很大的潜力。

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