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Determination of newborn jaundice level by transcutaneous bilirubin measurement

机译:经皮胆红素测定法测定新生儿黄疸

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Diffuse reflectance spectroscopy is a method for obtaining optical properties of skin to determine the biochemical and physiological information. Transcutaneous bilirubin (TcB) measurement is a practice that uses reflectance spectroscopy based on visible spectrum to determine the jaundice level in newborns. It has some advantages over total serum bilirubin (TSB) such as being non-invasive, non-infectious, painless, instantaneous etc. In this study, it is aimed to develop a jaundice level prediction algorithm with artificial neural network (ANN) by using the diffuse reflectance spectra that are obtained by an in-house developed device. For this purpose, TcB and TSB measurements were taken from 314 infants and the algorithm was developed. The predicted jaundice levels were compared with the TSB results in terms of root mean squared error (RMSE) and correlation (r). The developed algorithm gave satisfying results in the sense of accurately predicting the jaundice level. The obtained r value between TSB and TcB is nearly 0.94.
机译:漫反射光谱法是获得皮肤的光学特性以确定生化和生理信息的方法。经皮胆红素(TcB)测量是一种使用基于可见光谱的反射光谱法确定新生儿黄疸水平的实践。与总血清胆红素(TSB)相比,它具有无创,无感染,无痛,瞬时等优点。由内部开发的设备获得的漫反射光谱。为此,对314名婴儿进行了TcB和TSB测量,并开发了算法。将预测的黄疸水平与TSB结果进行了均方根误差(RMSE)和相关性(r)的比较。从准确预测黄疸程度的意义上说,所开发的算法给出了令人满意的结果。在TSB和TcB之间获得的r值接近0.94。

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