• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Society for Biomaterials annual meeting and exposition >'Ruffled border' formation on a CaP-free substrate: a first step towards osteoclast-recruiting bone-grafts materials able to re-establish bone turn-over
【24h】

'Ruffled border' formation on a CaP-free substrate: a first step towards osteoclast-recruiting bone-grafts materials able to re-establish bone turn-over

机译：在不含CaP的基材上形成“皱纹边界”：迈向破骨细胞招募能够重建骨翻转的骨移植材料的第一步

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

CaP-free El001 (1k) is a suitable substrate for osteoclast culture. The transparency of ElOOl(lk) in combination with high resolution confocal imaging enabled visualization of morphological features of osteoclast activation such as the formation of the "actin ring" and the "ruffled border", which previously required destructive forms of imaging such as transmission electron microscopy. The significance of these results is twofold: (1) ElOOl(lk) is suitable for osteoclast attachment and supports osteoclast maturation, making it a base polymer that can be further modified to optimize stimulation of BTO and (2) the transparency of this polymer makes it a suitable analytical tool for studying osteoclast behavior.
机译：不含CaP的El001（1k）是破骨细胞培养的合适底物。 ElOOl（lk）的透明性与高分辨率共聚焦成像相结合，可以可视化破骨细胞活化的形态特征，例如“肌动蛋白环”和“皱边”的形成，而以前需要破坏性的成像形式，例如透射电子显微镜检查。这些结果的意义有两个方面：（1）El00l（lk）适合破骨细胞附着并支持破骨细胞成熟，使其成为基础聚合物，可以对其进行进一步修饰以优化BTO的刺激;（2）该聚合物的透明性它是研究破骨细胞行为的合适分析工具。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号