Glycosaminoglycan Incorporation into Particle-Based Hydrogels for Enhanced Articular Cartilage Regeneration

机译：糖胺聚糖掺入基于颗粒的水凝胶中以增强关节软骨的再生

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The results of this study demonstrate the potential provided by incorporation of GAGs, such as chondroitin sulfate, into MAP hydrogel for accelerated cartilage regeneration. The CSMAP gel displayed a similar Young's modulus, more-negative zeta potential, desired CS retainment, effective cell infiltration, and early signs of chondrogenesis. Ongoing studies are pressing forward to establish statistical significance of incorporating CS (versus no CS and untreated) in void filling and cellular integration.

机译：这项研究的结果表明，通过将GAG（例如硫酸软骨素）掺入MAP水凝胶中，可以加速软骨再生。 CSMAP凝胶显示出相似的杨氏模量，更负的Zeta电位，所需的CS保留，有效的细胞浸润和软骨形成的早期迹象。正在进行的研究正在推动建立在空隙填充和细胞整合中纳入CS的统计意义（相对于没有CS和未经处理的）。

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《Society for Biomaterials annual meeting and exposition》|2019年|850-850|共1页
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Blaise N. Pfaff; Nicholas J. Cornell; Patrick S. Cottier; Christine Schaeffer; Brent DeGeorge; Donald Griffin;
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1. Contrast-enhanced CT of Articular Cartilage: Experimental Study for Quantification of Glycosaminoglycan Content in Articular Cartilage. [J] . Yoo HJ, Hong SH, Choi JY, Radiology . 2011,第3期

机译：关节软骨CT增强扫描：量化关节软骨中糖胺聚糖含量的实验研究。
2. Enhanced articular cartilage regeneration with SIRT1-activated MSCs using gelatin-based hydrogel [J] . Seong Mi Choi, Kyoung-Mi Lee, Seung Bae Ryu, Cell death & disease. . 2018,第9期

机译：使用明胶的水凝胶改变具有SIRT1激活的MSC的关节软骨再生
3. Enhancing the stiffness of collagen hydrogels for delivery of encapsulated chondrocytes to articular lesions for cartilage regeneration [J] . Omobono Mark A., Zhao Xing, Furlong Michael A., Journal of biomedical materials research, Part A . 2015,第4期

机译：增强胶原蛋白水凝胶的刚度，以将封装的软骨细胞递送至关节病变处，以进行软骨再生
4. Glycosaminoglycan Incorporation into Particle-Based Hydrogels for Enhanced Articular Cartilage Regeneration [C] . Blaise N. Pfaff, Nicholas J. Cornell, Patrick S. Cottier, Society for Biomaterials annual meeting and exposition . 2019

机译：糖胺聚糖掺入颗粒基水凝胶，用于增强关节软骨再生
5. Engineering articular cartilage using newly developed carrageenan based hydrogels =Desenvolvimento de novos hidrogéis baseados em carragenina para aplicação em engenharia de cartilagem articular [D] . Popa, Elena Geta. 2013

机译：使用新开发的基于角叉菜胶的水凝胶工程化关节软骨=开发用于关节软骨工程的新的基于角叉菜胶的水凝胶
6. Enhanced articular cartilage regeneration with SIRT1-activated MSCs using gelatin-based hydrogel [O] . Seong Mi Choi, Kyoung-Mi Lee, Seung Bae Ryu, 2018

机译：基于明胶的水凝胶通过SIRT1激活的MSC增强关节软骨再生
7. The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells [O] . Riccardo Levato, William R. Webb, Iris A. Otto, 2017

机译：墨水中的生物：用生物印象水凝胶和关节软骨衍生的祖细胞的软骨再生

Glycosaminoglycan Incorporation into Particle-Based Hydrogels for Enhanced Articular Cartilage Regeneration

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