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Medical Cyclotron ~(18)F Radionuclides Production Simulation in a Liquid Target with 16.5 MeV Proton Beam

机译:16.5 MeV质子束在液体靶中的医用回旋加速器〜(18)F放射性核素生产模拟

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Medical cyclotrons are devices dedicated to the production of radionuclides administered to patients to perform either diagnostics or therapy. The ~(18)F used for the synthesis of fluorodeoxyglucose (~(18)FDG) is produced by the bombardment of water enriched with ~(18)O target by a beam of protons. In the present study, the production of ~(18)F was simulated in order to test GATE's effectiveness and its ability to simulate the ~(18)F production next to other elements possibly produced during the bombardment. The technique is to vary the irradiation parameters using the GATE software. GATE is a very powerful simulation tool; it is widely used in medical imaging and radiotherapy applications. The results of this task confirm the reliability of the GATE Monte Carlo simulation in the modeling of the radioisotope production system based on the results found, which is promising for diagnostic imaging studies and extended therapeutic applications.
机译:医用回旋加速器是专用于生产放射性核素的设备,这些放射性核素被给予患者以进行诊断或治疗。用于合成氟代脱氧葡萄糖(〜(18)FDG)的〜(18)F是通过质子束轰击富含〜(18)O靶的水而产生的。在本研究中,模拟〜(18)F的产生以测试GATE的有效性及其模拟轰击期间可能产生的其他元素旁边模拟〜(18)F产生的能力。该技术是使用GATE软件更改辐照参数。 GATE是一个非常强大的仿真工具。它被广泛用于医学成像和放射治疗应用。这项任务的结果基于所发现的结果,证实了GATE Monte Carlo模拟在放射性同位素生产系统建模中的可靠性,这对于诊断成像研究和扩展的治疗应用是有前途的。

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