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Validation of a software platform for 2D and 3D phase contrast imaging: Preliminary subjective evaluation

机译：验证用于2D和3D相衬成像的软件平台：初步的主观评估

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A complete software platform based on anthropomorphic breast models used with both planar and three-dimensional phase contrast breast imaging is presented and subjectively validated. For the development of the platform, tests with three anthropomorphic breast phantoms, available both in computational and physical form, were designed and implemented. The models are characterised with different complexity: two phantoms are with spheres and one anthropomorphic. Further on, two of the physical breast models were created with the use of 3D printing techniques. These phantoms with thickness of 40 mm and 31 mm, respectively, were based on digital phantoms created with in-house developed software tools. The third physical breast phantom is the L1 phantom developed at Katholieke Universiteit Leuven with 58 mm thickness. Based on this physical phantom, a computational one was created. The three physical breast phantoms were imaged at ID17 biomedical imaging line at ESRF. Two acquisition setups were used: planar and limited angle tomography modes. Simulated and experimental planar and three-dimensional images were compared in terms of visual reproducibility. Results showed that phantoms characterised with more simple structure produce subjectively similar experimental and simulation appearance in terms of object reproduction and similar edge effects. The thicker phantom demonstrated lower visual coincidence between the two types of planar images, due to higher thickness and higher energy incident beam. The results of this study will be used in the design of new experimental study, to be conducted at lower incident beam energy as well as improving the modelling of phase contrast imaging by using Monte Carlo techniques.
机译：提出并主观验证了基于拟人化乳房模型的完整软件平台，该模型与平面和三维相位对比乳房成像一起使用。为了开发该平台，设计并实施了三种拟人化的乳房幻像的测试，这些幻像以计算形式和物理形式均可用。这些模型的特点是具有不同的复杂性：两个幻像带有球形，一个拟人化。进一步，使用3D打印技术创建了两个物理乳房模型。这些幻影的厚度分别为40毫米和31毫米，是基于使用内部开发的软件工具创建的数字幻影。第三种物理乳房幻像是鲁汶大学（Kathholieke鲁汶）开发的L1幻像，厚度为58毫米。基于此物理模型，创建了计算模型。在ESRF的ID17生物医学成像线对这三个物理乳房模型进行了成像。使用了两种采集设置：平面和有限角度层析成像模式。在视觉再现性方面比较了模拟和实验的平面和三维图像。结果表明，具有更简单结构特征的体模在对象复制和相似的边缘效果方面产生主观上相似的实验和模拟外观。由于较高的厚度和较高的入射光束，较厚的体模显示出两种平面图像之间的视觉重合度较低。这项研究的结果将用于新的实验研究的设计中，该研究将在较低的入射光束能量下进行，并通过使用蒙特卡洛技术改进相衬成像的建模。

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