首页> 外文会议>Annual International Conference of the IEEE Engineering in Medicine and Biology Society >Effects of functional electrical stimulation on neuromuscular function after targeted muscle reinnervation surgery in rats*
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Effects of functional electrical stimulation on neuromuscular function after targeted muscle reinnervation surgery in rats*

机译:功能性电刺激对大鼠肌肉再定向手术后神经肌肉功能的影响*

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the purpose of targeted muscle reinnervation (TMR) surgery is to provide more electromyography information for prosthetic control by reconstructing the deconstructed structure between the distal nerve and the stump muscle. Functional electrical stimulation (FES) of denervated muscles or proximal nerve stump after peripheral nerve surgery can effectively promote nerve regeneration and muscle function recovery. This pilot divided SD adult male rats into normal control group, denervation group, TMR group, and FES group according to whether they received TMR surgery and whether they received FES after surgery. The results showed that low-frequency electrical stimulation treatment could effectively promote transplanted nerve regeneration and significantly enhances motor function of target muscles.Clinical Relevance—This experiment successfully established TMR rat models, and explored the recovery of injured neuromuscular function by using electrodes implanted intramuscularly and analyzing myoelectric signals, and the use of low-frequency electrical stimulation treatment had a positive effect on the regeneration of the transplanted nerve.
机译:定向肌肉再支配(TMR)手术的目的是通过重建远端神经和残端肌肉之间的解构结构,为修复控制提供更多的肌电图信息。周围神经手术后的失神经肌肉或近端神经残端的功能性电刺激(FES)可以有效地促进神经再生和肌肉功能的恢复。根据是否接受TMR手术以及术后是否接受FES,该飞行员将SD成年雄性大鼠分为正常对照组,神经支配组,TMR组和FES组。结果表明,低频电刺激治疗可有效促进移植神经再生,并显着增强目标肌肉的运动功能。分析肌电信号,并采用低频电刺激治疗对移植神经的再生有积极作用。

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