首页> 外文会议>5th International Photodynamic Association Biennial Meeting >New approach for treatment of advanced malignant tumors: combination ofchemotherapy and photodynamic therapy,
【24h】

New approach for treatment of advanced malignant tumors: combination ofchemotherapy and photodynamic therapy,

机译:治疗晚期恶性肿瘤的新方法:化学疗法和光动力疗法的结合,

获取原文

摘要

Abstract: Eighty-three patients suffering from moderate or advanced malignant tumors were treated by combined chemotherapy and photodynamic therapy (PDT) in our hospital. The short term result of such management is very promising, the effectiveness seems to be nearly 100% and the general responsive rate is 79.5% (CR $PLU PR). If compared with another group of 84 similar patients whom were treated with PDT alone, the short term efficacy is 85.7% while the general response rate is 54.7% (P $LS 0.01), there is a significant statistic. The better result of the combined approach is probably due to the action of the chemotherapeutic agent, potentially blocking the mitosis of the cellular cycle at certain phases of the cancer cells, making the cell membrane become more permeable to the photochemical agent, HPD, and eliciting a better cancerocidal effect. !0
机译:【摘要】我院对83例中,晚期恶性肿瘤患者进行了联合化学疗法和光动力疗法(PDT)的治疗。这种管理的短期结果是非常有希望的,其有效性似乎接近100%,总体响应率为79.5%(CR $ PLU PR)。如果与另一组单独接受PDT治疗的84例相似患者进行比较,短期疗效为85.7%,而总缓解率为54.7%(P $ LS 0.01),则有统计学意义。组合方法的更好结果可能是由于化学治疗剂的作用,潜在地阻止了癌细胞某些阶段的细胞周期的有丝分裂,使细胞膜对光化学剂,HPD的渗透性更高并引起更好的杀癌效果。 !0

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号